Revision as of 08:30, 7 October 2010

E. lemming: remote controlled E. coli by ETH Zurich

Project

What is E. lemming?

E. lemming is the 2010 iGEM project of ETH Zurich. We intend to control movement of a single E. coli bacterium by hijacking chemotaxis and monitoring of position and direction of the bacterium by image processing algorithms, which are linked to a controller device. Find out more by watching an animation of the project overview!

Project
What is E. lemming?
E. lemming is the 2010 iGEM project of ETH Zurich. We intend to control movement of a single E. coli bacterium by hijacking chemotaxis and monitoring of position and direction of the bacterium by image processing algorithms, which are linked to a controller device. Find out more by watching an animation of the project overview!
Molecular Mechanism
How does it work?
By coupling chemotactic receptor proteins to a novel synthetic light-sensitive spatial localization system, their activity can be controlled reversibly. To find out more about our project on the molecular level, watch an animation here.
Controlling
How is it controlled?
Tumbling / directed flagellar movement rates are monitored by image processing algorithms, which are linked to the light-pulse generator. This means that E. coli tumbling is induced or suppressed simply by pressing a light switch! Click here to found out more!
Biology & Wet Laboratory
How is it implemented?
Informations regarding the biological implementation and an overview about the conducted wet laboratory experiments can be found in this section.
Molecular Modeling
How does modeling help?
Molecular modeling supports analysis of biological systems since the advent of synthetic biology. Find out, how this not only supported wet laboratory experiments by providing time and effort alleviating parameter selection, but also provided a test bench for the information processing part.
Information Processing
How is it controlled in detail?
Implementation of a comprehensive information processing workflow for controlling E. lemming was achieved by combination of microscopy, image processing, cell detection and a controller. Find out more about how this not only created E. lemming but also created a new application for synthetic biology: Gaming!

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 						<small>How does modeling help?</small>
-						<p><a href="https://2010.igem.org/Team:ETHZ_Basel/Modeling" class="teaserlink">Molecular modeling supports analysis of biological systems since the advent of synthetic biology. Find out, how for E. lemming, this not only supported wet laboratory experiments by providing time and effort alleviating parameter selection, but also provided a test bench for the information processing part.</a> </p>
+						<p><a href="https://2010.igem.org/Team:ETHZ_Basel/Modeling" class="teaserlink">Molecular modeling supports analysis of biological systems since the advent of synthetic biology. Find out, how this not only supported wet laboratory experiments by providing time and effort alleviating parameter selection, but also provided a test bench for the information processing part.</a> </p>
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Team:ETHZ Basel

From 2010.igem.org

Revision as of 08:30, 7 October 2010

E. lemming: remote controlled E. coli by ETH Zurich

Project

Project

Molecular Mechanism

Controlling

Biology & Wet Laboratory

Molecular Modeling

Information Processing

Sponsors