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Team:ETHZ Basel/Project/Movie
From 2010.igem.org
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= Project Overview = | = Project Overview = | ||
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| + | <div class="center"><div class="thumb tnone"><div class="thumbinner" style="width:662px;"> | ||
| + | <iframe title="YouTube video player" class="youtube-player" type="text/html" width="660" height="530" src="http://www.youtube.com/embed/XoWI-fxdo74" frameborder="0"></iframe> | ||
| + | <div class="thumbcaption"><div class="magnify"><a href="http://www.youtube.com/watch?v=XoWI-fxdo74" class="external" title="Enlarge"><img src="/wiki/skins/common/images/magnify-clip.png" width="15" height="11" alt="" /></a></div><b>Molecular mechanism of E. lemming.</b> This animation illustrates the molecular mechanism upon light induction of E. lemming.</div></div></div></div> | ||
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E. lemming aims to modify the chemotaxis property of E.coli such that, instead of response to a chemical attractant or repellent, the bacterium responds to a light stimulus. Furthermore, this light sensitivity is used to control E.coli’s movement by deciding, at any given time, which type of motion the bacterium will adopt (tumbling or straight run). This leads to a controllable E.coli, which can move to a defined direction, as a result of the combination of tumbling and straight run. The bacteria in the experiment are imaged and, by image processing, the position of a single tracked cell is inferred. By activating a light switch, the user decides whether the bacterium should continue running or should change direction. | E. lemming aims to modify the chemotaxis property of E.coli such that, instead of response to a chemical attractant or repellent, the bacterium responds to a light stimulus. Furthermore, this light sensitivity is used to control E.coli’s movement by deciding, at any given time, which type of motion the bacterium will adopt (tumbling or straight run). This leads to a controllable E.coli, which can move to a defined direction, as a result of the combination of tumbling and straight run. The bacteria in the experiment are imaged and, by image processing, the position of a single tracked cell is inferred. By activating a light switch, the user decides whether the bacterium should continue running or should change direction. | ||
= Strategy = | = Strategy = | ||
Revision as of 14:17, 5 October 2010
Project Overview
E. lemming aims to modify the chemotaxis property of E.coli such that, instead of response to a chemical attractant or repellent, the bacterium responds to a light stimulus. Furthermore, this light sensitivity is used to control E.coli’s movement by deciding, at any given time, which type of motion the bacterium will adopt (tumbling or straight run). This leads to a controllable E.coli, which can move to a defined direction, as a result of the combination of tumbling and straight run. The bacteria in the experiment are imaged and, by image processing, the position of a single tracked cell is inferred. By activating a light switch, the user decides whether the bacterium should continue running or should change direction.
