Team:TU Delft/Team/previous-teams
From 2010.igem.org
(→TU Delft iGEM Team 2009 - BACTERIAL RELAY RACE) |
(→TU Delft iGEM Team 2008 - ENGINEERING A BIOTHERMOMETER) |
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Read more on the [https://2009.igem.org/Team:TUDelft TU Delft iGEM Team 2009 Wiki] | Read more on the [https://2009.igem.org/Team:TUDelft TU Delft iGEM Team 2009 Wiki] | ||
+ | [[Image:System.png|thumb|300px|right|Black box representation of the biothermometer, with temperature as input and color as output. The system can be split into two subsystems: A temperature sensitive input system and a color producing output system. The temperature sensitive input system works as a switch, switching on the output system at a certain temperature.]] | ||
===TU Delft iGEM Team 2008 - ENGINEERING A BIOTHERMOMETER=== | ===TU Delft iGEM Team 2008 - ENGINEERING A BIOTHERMOMETER=== | ||
The teams goal was to construct a temperature-sensing bacteria Escherichia coli that changes color at different temperatures. Such a thermometer can be applied e.g. as a temperature reporter system in large-scale fermentations, or as a temperature-inducible protein production system. | The teams goal was to construct a temperature-sensing bacteria Escherichia coli that changes color at different temperatures. Such a thermometer can be applied e.g. as a temperature reporter system in large-scale fermentations, or as a temperature-inducible protein production system. |
Revision as of 09:46, 13 September 2010
This is the third year the TU Delft is joining the iGEM competition. Considering the success of previous teams, the expectations are high.
TU Delft iGEM Team 2009 - BACTERIAL RELAY RACE
The teams aim was to build an improved cell to cell communication system. They were attempting to construct an E.coli strain which is capable of passing a GFP (Green Fluorescent Protein) signal through conjugation. This mechanism provides the ability of transferring genetic material between bacteria through direct cell to cell contact. A delayed self destructing mechanism caused the destruction of the genetic material of the donor cell after the transfer. The idea is comparable to a relay race, and an illustrative animation discribing this project can be found to the right.
Reward: Gold medal and award for ‘Best Information Processing Project’.
Read more on the TU Delft iGEM Team 2009 Wiki
TU Delft iGEM Team 2008 - ENGINEERING A BIOTHERMOMETER
The teams goal was to construct a temperature-sensing bacteria Escherichia coli that changes color at different temperatures. Such a thermometer can be applied e.g. as a temperature reporter system in large-scale fermentations, or as a temperature-inducible protein production system.
If the temperature exceeds a certain threshold, a sensitive RNA structure opens up and the ribosome (a molecular protein manufacturing machine) can bind to the RNA. This results in the production of a color compound - Farnesyl PyroPhosphate (FPP).
Reward: Golden medal and the trophy for the ‘Best Wiki’.
Read more on the TU Delft iGEM Team 2008 Wiki