Team:Cambridge/Bioluminescence
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{{:Team:Cambridge/Templates/headerbar|colour=#96d446|title=Bioluminescence: Introduction}} | {{:Team:Cambridge/Templates/headerbar|colour=#96d446|title=Bioluminescence: Introduction}} | ||
- | The Cambridge team for this year's iGEM is aiming to improve the production of light by engineered micro-organisms. We are pursuing a number of lines of enquiry to achieve this | + | The Cambridge team for this year's iGEM is aiming to improve the production of light by engineered micro-organisms. We are pursuing a number of lines of enquiry to achieve this: |
* <strong>Bacterial luciferases</strong> from <i>Vibrio fischeri</i>, and <i>Photorhabdus luminescens</i> | * <strong>Bacterial luciferases</strong> from <i>Vibrio fischeri</i>, and <i>Photorhabdus luminescens</i> | ||
* <strong>Firefly luciferases</strong> from <i>Photinus pyralis</i>, and <i>Luciola cruciata</i>, including mutants with increased light output and different colours | * <strong>Firefly luciferases</strong> from <i>Photinus pyralis</i>, and <i>Luciola cruciata</i>, including mutants with increased light output and different colours | ||
- | * Implementation of the firefly <b>luciferin regenerating enzymes (LRE)</b> from the above species into E. coli | + | * Implementation of the firefly <b>luciferin regenerating enzymes (LRE)</b> from the above species into <i>E. coli</i>, this enzyme is believed to |
+ | [[Image:Cam-luci-cycle.jpg|center|500px]] | ||
+ | |||
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Revision as of 19:48, 3 August 2010
Bioluminescence: Introduction
The Cambridge team for this year's iGEM is aiming to improve the production of light by engineered micro-organisms. We are pursuing a number of lines of enquiry to achieve this:
- Bacterial luciferases from Vibrio fischeri, and Photorhabdus luminescens
- Firefly luciferases from Photinus pyralis, and Luciola cruciata, including mutants with increased light output and different colours
- Implementation of the firefly luciferin regenerating enzymes (LRE) from the above species into E. coli, this enzyme is believed to