Team:Harvard/vectors/agro

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introduction to agrobacteria

Scientists have known since 1907 that agrobacteria cause tumor formation and other horticultural abnormalities in plants, but it was not until the 1970's that it was discovered that agrobacteria induce these changes by incorporating part of their own genetic material into the plant genome. Using genes encoded on a plasmid separate from the bacterial chromosome, called the tumor inducing (Ti) plasmid, agrobacteria bind to plant cells and transfer segments of DNA into the plant, which are then expressed by the plant to produce hormones to stimulate uncontrolled growth, which induce tumor formation, and to produce opines, amino acid derivatives which serve as a source of carbon and nitrogen for the agrobacteria.