Team:Cambridge/Description

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(Preliminary description)
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=Preliminary description=
=Preliminary description=
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The Cambridge team has been brainstorming ideas.  We have narrowed our ideas down to two possible projects:
 
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* Bioluminescence and quiescence in E. coli
 
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* Implementing an ELISA-like diagnostic test in bacteria
 
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We intend shortly to settle on one of these ideas and to produce biobricks and proof-of-concept systems, then measure and characterise them.
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The Cambridge iGEM team will be investigating bioluminescence and quiescence in ''E. coli''. Our broad targets will be to:
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* Maximise light output from bacterial or firefly luciferase
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* Characterise a device with a known transfer function between PoPs input and light output
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* Partially reconstruct the biosynthetic pathway of luciferin
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* Create a biobrick for the induction of quiescence in ''E. coli''
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* Improve the existing switching mechanism for quiescence
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Our focus will shift over the course of the project, and objectives may be added and removed, but the end goal ideally is to have a strain of ''E. coli'' which will stop growing and start emitting light at on a trigger.
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Revision as of 10:50, 16 July 2010