Team:The Citadel-Charleston

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Appetuners: A System for the Expression and Control of Appetite Regulation Peptides in E.coli

The 2010 Citadel-Charleston iGEM team invites you to join us as we explore a novel healthcare solution to obesity and weight-related ailments: influencing the desire to eat through an engineered strain of intestinal microflora. Our team has focused research and development on Peptide Tyrosine Tyrosine (PYY), a peptide which could permit microorganisms native to the gastrointestinal tract to interact with the central nervous system and manipulate the perception of hunger. The Citadel-Charleston Team has worked to express the PYY3-36 peptide in E.coli and to ensure that its expression is strictly controlled by means of a cellular population limit.

News and Updates

November 22, 2010: The Citadel iGEM Wiki has been updated. A number of edits, both technical and aesthetic, have been made to make the wiki more useful to future visitors and iGEM teams.

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        	  align=left><p class="BodyText">Appetuners: A System for the Expression and Control of Appetite Regulation <span id="lw_1290449503_0">Peptides</span> in <em>E.coli</em></p>
-<p class="BodyText">The   2010 Citadel-Charleston iGEM team invites you to join us as we explore a   novel healthcare solution to obesity and weight-related ailments:   influencing the desire to eat through an engineered strain of intestinal   microflora.  Our team has focused research and development on <span id="lw_1290449503_2">Peptide</span> <span id="lw_1290449503_3">Tyrosine</span> Tyrosine (PYY), a peptide which could permit microorganisms native to the <span id="lw_1290449503_4">gastrointestinal tract</span> to interact with the <span id="lw_1290449503_5">central nervous system</span> and manipulate the perception of hunger.  The Citadel-Charleston Team has worked to express the PYY3-36 peptide in <em>E.coli</em> and to ensure that its expression is strictly controlled by means of a cellular population limit.</p>
+<p class="BodyText">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The 2010 Citadel-Charleston iGEM team invites you to join us as we explore a   novel healthcare solution to obesity and weight-related ailments:   influencing the desire to eat through an engineered strain of intestinal   microflora.  Our team has focused research and development on <span id="lw_1290449503_2">Peptide</span> <span id="lw_1290449503_3">Tyrosine</span> Tyrosine (PYY), a peptide which could permit microorganisms native to the <span id="lw_1290449503_4">gastrointestinal tract</span> to interact with the <span id="lw_1290449503_5">central nervous system</span> and manipulate the perception of hunger.  The Citadel-Charleston Team has worked to express the PYY3-36 peptide in <em>E.coli</em> and to ensure that its expression is strictly controlled by means of a cellular population limit.</p>
 <p class="BodyText">&nbsp;</p>
 <p class="TitleSection">News and Updates</p>