Team:Sheffield/Safety

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The Sheffield iGEM 2010 project came under a much larger EPSRC pathogen detection and water industry project. This dealt with approval from the University safety committee and also included many risk assessments and detailed the use of GM organisms. The strains of E.coli used were none pathogenic and designed to not survive well outside of the laboratory environment to reduce risk to both researcher and to the public/environment. To supplement researcher safety, every team member underwent safety and waste disposal training before performing any experiments in the lab and the team was supervised throughout the project by more experienced research scientists. None of the biobricks designed by the team had any safety implications and the project was designed as such to avoid toxins from Vibrio cholera . Some considerations were given to the final iColi product, and it was decided that this would have to be kept seperate to the public drinking supply and well contained. It was also suggested that it might be beneficial to include some form of suicide plasmid within the final product to reduce any risk from escape.

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-Safety was important throughout the Sheffield iGEM 2010 iColi project. All researchers received waste disposal and safety training prior to performing work in the lab. In addition the team were always supervised by a more experienced research scientist.
+The Sheffield iGEM 2010 project came under a much larger EPSRC pathogen detection and water industry project. This dealt with approval from the University safety committee and also included many risk assessments and detailed the use of GM organisms.
-None of the biobricks raised any safety issues.
+The strains of <i> E.coli </i> used were none pathogenic and designed to not survive well outside of the laboratory environment to reduce risk to both researcher and to the public/environment. To supplement researcher safety, every team member underwent safety and waste disposal training before performing any experiments in the lab and the team was supervised throughout the project by more experienced research scientists.
-The Sheffield iGEM project came under a much larger pathogen detection project conducted at the university of which the biosafety group had approved.
+None of the biobricks designed by the team had any safety implications and the project was designed as such to avoid toxins from <i> Vibrio cholera </i>. Some considerations were given to the final iColi product, and it was decided that this would have to be kept seperate to the public drinking supply and well contained. It was also suggested that it might be beneficial to include some form of suicide plasmid within the final product to reduce any risk from escape.
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