Team:NYMU-Taipei
From 2010.igem.org
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** provide speedy ways to report and stop gene expression. | ** provide speedy ways to report and stop gene expression. | ||
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Latest revision as of 20:31, 27 October 2010
- Default display
- Your Promoter
- Your Promoter
- Your Protein
- Your Protein
- Speedy mRNA Reporter
- Speedy mRNA Reporter
- Speedy Protein Reporter
- Speedy Protein Reporter
- Speedy Switch
- Speedy Switch
- Speedy Protein Degrader
- Speedy Protein Degrader
Home | Project Overview | Speedy reporter | Speedy switch | Speedy protein degrader | Experiments and Parts | Applications | F.A.Q | About Us |
SpeedyBac
Provide a faster assay system for exploring the design rules of synthetic biology.
There are already many genetic parts in the Biobrick Parts Registry and the numbers are growing fast. Every year every igem teams will build genetic circuits based on the parts at partsregistry. But where are the design rules to put these parts into circuits of devices and systems? Apparently, the "Assembly Standards" listed at the partsregistry are only used to connect compatible restriction enzyme cutting sites. They are NOT designing principles. Our iGEM team is very interested in the detailed design rules played in the central dogma; especially those principles for connecting mRNA translation to protein folding. Traditionally, we know about the circuits we made are working or not mostly through the expression of reporter genes. However, it would be much helpful if we could have information of quantitative description of gene expression in both space and time. For these reasons and for the future development of synthetic biology, we just have to speed up the experimental explorations of design rules.
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To achieve our specific aim, we have designed a novel reporting device (Speedy reporter) for quickly detectin and measuring the mRNA location and quantity, it can also be used for protein detection. And we design a novel switch (Speedy switch) for control the mRNA translation of gene expression. We have also designed a faster degradation device (Speedy protein degrader); it allows us to regulate the degradation time for studying the mRNAs without the interference from translation and quickly stopping the gene expression.
The official web pages of our school - National Yang Ming University (NYMU):
Click the following two links to see The Beauty of NYMU
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