Team:GeorgiaTech/Systems Modeling

From 2010.igem.org

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<p>3) We solved for boundary conditions by solving two temperature profile   equations simultaneously in MATLAB<br />
<p>3) We solved for boundary conditions by solving two temperature profile   equations simultaneously in MATLAB<br />
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  Required: Slide in MATLAB<br />
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<center><img src="https://static.igem.org/mediawiki/2010/e/e4/MATLAB.png" width="" height="" img style="border: 2px solid white"></center>
<center><img src="https://static.igem.org/mediawiki/2010/e/e4/MATLAB.png" width="" height="" img style="border: 2px solid white"></center>
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<center>Figure 1. This figure shows the temperature profile of bacteria and  the solid growth media as a function of height. In E. coli, temperature drops  quadratically, and it drops linearly in agarose. This is because of the heat  generation term included within the Poisson equation developed to describe heat  transfer in E. coli. The total drop of temperature at steady state across the  height of bacterial colony and agarose is approximately 0.1 K. </p></center>
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<center><i>Figure 1. This figure shows the temperature profile of bacteria and  the solid growth media as a function of height. In E. coli, temperature drops  quadratically, and it drops linearly in agarose. This is because of the heat  generation term included within the Poisson equation developed to describe heat  transfer in E. coli. The total drop of temperature at steady state across the  height of bacterial colony and agarose is approximately 0.1 K. </p></i></center>
<p><strong>IV) Heat transport in bacterial  colony 2D and 3D (using COMSOL) </strong><br />
<p><strong>IV) Heat transport in bacterial  colony 2D and 3D (using COMSOL) </strong><br />
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  Required: slide on 2d comsol<br />
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<center><img src="https://static.igem.org/mediawiki/2010/9/9c/2Dmodel.png" width="" height="" img style="border: 2px solid white"></center>
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  Required: slide on 3d comsol<br />
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<p>Figure 2.</p>
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SLIDE  DESCRIPTION: This figure as well as the previous were developed in  COMSOL. They depict 2D and 3D heat transfer in bacterial colony and agarose.  The difference between peak temperatures in both scenarios did not differ by  more than 0.006K which indicates that a 2D control volume may provide  sufficiently accurate representation for heat transport modeling. In a 2D  control volume, heat is transferred radially to the environment. If high aspect  ratio is implemented, as in case of a uniform stretch of bacterial colony  formed on a petri dish, then 1D control volume will be sufficient. </p>
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<center><img src="https://static.igem.org/mediawiki/2010/3/34/3Dmodel.png" width="" height="" img style="border: 2px solid white"></center>
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<p>Figure 3.</p>
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<center><p>Figure 2 and 3 were developed in  COMSOL. They depict 2D and 3D heat transfer in bacterial colony and agarose.  The difference between peak temperatures in both scenarios did not differ by  more than 0.006K which indicates that a 2D control volume may provide  sufficiently accurate representation for heat transport modeling. In a 2D  control volume, heat is transferred radially to the environment. If high aspect  ratio is implemented, as in case of a uniform stretch of bacterial colony  formed on a petri dish, then 1D control volume will be sufficient. </p>
<p><strong>V) Conclusions:</strong></p>
<p><strong>V) Conclusions:</strong></p>
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Revision as of 19:26, 27 October 2010