Team:Johns Hopkins

From 2010.igem.org

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*JHU HiT Center
*JHU HiT Center
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<big>'''Major Accomplishments'''</big>
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<big>'''Our Accomplishments'''</big>
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*Extended previous work in voltage sensitivity (Valencia 2009) in S. cerevisiae
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*We have extended previous work on voltage sensitivity (Valencia 2009) in S. cerevisiae, bringing the response from the biochemical domain into the transcriptional.
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*Constructed of 7 voltage-activated UASs of varying sensitivity
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*We constructed a library of 7 voltage-activated yeast upstream activation sequences with varying sensitivity.
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*[ONGOING] Submitted 1 fully characterized voltage-activated promoter
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*We have characterized two full voltage-activated promoters for yeast.
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*The above elements have been submitted to the Parts Registry.
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*The have developed a model to describe the transcriptional response to voltage of our system.
[[Image:IGEM_Team_Photo.jpg|650px|center|thumb| JHU iGEM 2010]]
[[Image:IGEM_Team_Photo.jpg|650px|center|thumb| JHU iGEM 2010]]

Revision as of 06:38, 19 October 2010

JHU.

Johns Hopkins University

Our Project (in a sentence)...We are engineering Saccharomyces cerevisiae to be voltage-sensitive at the transcriptional level.
Our Team...We are a team of 9 undergraduate students deeply interested in synthetic biology. We hail from a variety of disciplines including, chemistry, biology and engineering. We’re a fresh new team with varying levels of experience united by our passion for science.

Our Sponsors

  • JHU Biology, esp. Dr. Beverly Wendland
  • JHU Biomedical Engineering, esp. Dr. Timothy McVeigh and Gail Spence
  • JHU Chemical and Biomolecular Engineering
  • JHU Alumni Foundation
  • JHU Provost’s Undergraduate Research Award
  • The Hodson Trust
  • JHU Integrated Imaging Center, esp. Dr. Richard McCarty and Erin Pryce
  • JHU Undergraduate Admissions, esp. Maggie Kennedy
  • JHU BAG
  • JHU HiT Center

Our Accomplishments

  • We have extended previous work on voltage sensitivity (Valencia 2009) in S. cerevisiae, bringing the response from the biochemical domain into the transcriptional.
  • We constructed a library of 7 voltage-activated yeast upstream activation sequences with varying sensitivity.
  • We have characterized two full voltage-activated promoters for yeast.
  • The above elements have been submitted to the Parts Registry.
  • The have developed a model to describe the transcriptional response to voltage of our system.
JHU iGEM 2010