Cell Line

The cell line used in this project is the human embryonic kidney cell line 293T .

Databases Search

The [http://www.ncbi.nlm.nih.gov/sites/entrez?db=ncbisearch NCBI GEO] and [http://www.ebi.ac.uk/arrayexpress/browse.html ArrayExpress] databases were extensively searched for environmental conditions leading to apoptosis in 293T cells and genes differentially expressed under these conditions. The following data was obtained:

[1] Reference one Geo [1] Reference one Geo [1] Reference one Geo [1] Reference one Geo [1] Reference one Geo [1] Reference one Geo

In order to understand gene regulation of apoptosis regulated genes the [http://rulai.cshl.edu/cgi-bin/TRED/tred.cgi?process=searchPromForm Transcriptional Regulatory Element Database (TRED)] was used to extract known promoters and the [http://string-db.org/ STRING] database for known and predicted protein-protein interactions. The lists of all known human transcription factors was downloaded from [http://www.introni.it/transcription_factors.html here] and [http://www.nature.com/nrg/journal/v10/n4/extref/nrg2538-s3.txt here].