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Team:UC Davis/Projects
From 2010.igem.org
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| - | var pHContent = "<br/><p class='header'>THE PROBLEM</p>Cellular machines are not isolated systems. They have an intimate relationship with their surroundings and must change with varying environmental conditions. To do this, they rely on sensory machinery to trigger internal fluctuations based on external stimuli such as light, chemical concentrations, etc. Sensors have been engineered for the E. coli chassis but one stimulus has been neglected: pH.<br/><br/> Cells thrive in a limited pH range; the optimal range for E. coli being 6-7. If the pH is much different than this, the cell must take action to survive. This | + | var pHContent = "<br/><p class='header'>THE PROBLEM</p>Cellular machines are not isolated systems. They have an intimate relationship with their surroundings and must change with varying environmental conditions. To do this, they rely on sensory machinery to trigger internal fluctuations based on external stimuli such as light, chemical concentrations, etc. Sensors have been engineered for the E. coli chassis but one stimulus has been neglected: pH.<br/><br/> Cells thrive in a limited pH range; the optimal range for E. coli being 6-7. If the pH is much different than this, the cell must take action to survive. This needs to be taken into account when designing cellular machines which are reactive to pH changes. A pH sensitive system from another organism would help keep the engineered response independent. This would allow the desired response to be separate from a stress response. <br/><br/><div style='text-align:center'><img src='https://static.igem.org/mediawiki/2010/a/ac/Mes_photo.jpg'></div>"; |
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Revision as of 23:25, 22 September 2010
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