Team:UC Davis/Projects

From 2010.igem.org

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var crosstalkContent = "<br/><div>In synthetic biology, the issue of crosstalk acts as a substantial barrier against developing fully-controlled biological systems.  Much like in the development of electrical systems where crosstalk causes harmful interference and unpredictable behavior, crosstalk prevents us from completely understanding how our biological constructs function, and quite often can affect the efficacy of these systems.  As such, it is clear that a method to computationally predict crosstalk in a given biological system would be a valuable scientific resource, and would effectively help minimize the negative effects of crosstalk.</div>";
var crosstalkContent = "<br/><div>In synthetic biology, the issue of crosstalk acts as a substantial barrier against developing fully-controlled biological systems.  Much like in the development of electrical systems where crosstalk causes harmful interference and unpredictable behavior, crosstalk prevents us from completely understanding how our biological constructs function, and quite often can affect the efficacy of these systems.  As such, it is clear that a method to computationally predict crosstalk in a given biological system would be a valuable scientific resource, and would effectively help minimize the negative effects of crosstalk.</div>";
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var pHContent="<br/>Cellular machines are not isolated systems.  They have an intimate relationship with their surroundings and must change with varying environmental conditions.  To do this, they rely on sensory machinery to trigger internal fluctuations based on external stimuli such as light, chemical concentrations, etc.  Sensors have been engineered for the E. coli chassis but one stimulus has been neglected: pH.<br/><br/>Using a two-component sensory kinase system from Agrobacterium tumefaciens, we have engineered a pH sensor for E. coli. 
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Revision as of 22:12, 21 September 2010

Spatial Oscillation pH Sensor Crosstalk Predictor
Spatial Oscillation
We would like to take a moment to thank all of our sponsors for their very generous donations, as we could not have done this without your help!

We would also like to thank and acknowledge:
Our Advisors
Marc Facciotti
Ilias Tagkopoulos
Technical Guidance
David Larsen
Andrew Yao
Visiting iGEMer
Jia Li of Zhejiang University (TEAM ZJU-China)
cI Promoter Screen
Drew Endy - Stanford
Thomas Schneider - NIH
Want to sponsor us? Send an email to mtfacciotti@ucdavis.edu to discuss various ways you can help! :)