Team:ESBS-Strasbourg
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Revision as of 15:02, 5 October 2010
Preliminary project description :
Inducible systems are used every day in labs, but chemical inducers have some limitations :
-Delayed induction (certain time between adding the chemical and seeing the result)
-Interference with host metabolism
-Only one way induction (once we add the chemical we cannot remove it)
-Chemicals are expensive
-Not always available
The aim of the ESBS-Strasbourg team is to create a “light controllable specific protein degradation system”, which will overpass the classical chemical induction limitations:
-Instant induction (no transcription and translation needed…)
-No interference with host metabolism
-Controllable (On/Off)
-Cheap
-Always available
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