Team:KAIST-Korea/FutureWorks

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Our final goal is to develop the '''universal diagnosis''' kit. But if we express more than one modified antigen receptor, signal from these receptors will be cross-talked. To prevent this crosstalk, we decided to selectively express specific modified receptor. Our first plan was to embed all gene of modified antigen receptors with promoter whose activators are different. But these idea have some problems. First of all, though we don't activate genes, there are expressions of genes. It is not possible to suppress gene 100%. So we planned to use the 'conjugation' of ''Schizosaccharomyces pombe''. So we will make 'antigen-binding' yeasts of different antigens and 'signal-transduction' yeast separately. And the diagnostician conjugate 'antigen-binding' yeast of certain antigen and common 'signal transduction' yeast before the diagnosis.
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== Our Final Goal ==
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Our final goal is to develop the '''universal diagnosis''' kit for every disease whose antibody is produced. To perform this goal, the yeast should express modified antigen receptor of wanted disease, STAT1 proteins and have GFP gene whose promoter have GAS element.
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== Disadvantage of '''All-in-One''' ==
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== Our Final Solution ==
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=== Life Cycle of ''S.pombe'' ===
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=== How to implement? ===
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Revision as of 10:27, 27 October 2010

 

Future Works



Our final goal is to develop the universal diagnosis kit. But if we express more than one modified antigen receptor, signal from these receptors will be cross-talked. To prevent this crosstalk, we decided to selectively express specific modified receptor. Our first plan was to embed all gene of modified antigen receptors with promoter whose activators are different. But these idea have some problems. First of all, though we don't activate genes, there are expressions of genes. It is not possible to suppress gene 100%. So we planned to use the 'conjugation' of Schizosaccharomyces pombe. So we will make 'antigen-binding' yeasts of different antigens and 'signal-transduction' yeast separately. And the diagnostician conjugate 'antigen-binding' yeast of certain antigen and common 'signal transduction' yeast before the diagnosis.

Contents

Our Final Goal

Our final goal is to develop the universal diagnosis kit for every disease whose antibody is produced. To perform this goal, the yeast should express modified antigen receptor of wanted disease, STAT1 proteins and have GFP gene whose promoter have GAS element.

Disadvantage of All-in-One

Our Final Solution

Life Cycle of S.pombe

How to implement?

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