Team:DTU-Denmark/Team
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<br><h4>Scientific Background</h4> | <br><h4>Scientific Background</h4> | ||
- | <p align="justify"><p align="justify">Mogens Kilstrup received his master degree in 1986 in biochemistry from the University of Copenhagen as well as his PhD degree in Molecular biology in 1992. After a Post doctoral position at DTU from 1993, he was appointed as associate professor in 2000 and advanced to | + | <p align="justify"><p align="justify">Mogens Kilstrup received his master degree in 1986 in biochemistry from the University of Copenhagen as well as his PhD degree in Molecular biology in 1992. After a Post doctoral position at DTU from 1993, he was appointed as associate professor in 2000 and advanced to professor in 2008 at Center for Systems Microbiology (CSM) at DTU.</p> |
Professor Kilstrup´s areas of expertise include gene regulation, microbial physiology, and molecular biology, with emphasis on medically and industrial important bacteria as ''Salmonella enterica'', ''Escherichia coli'' and ''Lactococcus lactis'' using both genetic and DNA recombinant techniques. Special expertise is found in the area of stress response and the genetics and physiology of nucleotide metabolism. Current major research project is the analysis of global regulatory networks (stress response) in ''L. lactis'', including physiological studies, proteomics (2D-gel electrophoresis coupled to mass spectrometry), transcriptomics (transcriptional analysis using DNA microarray), and biochemical characterization of regulatory systems. He is the author or co-author of more than 25 scientific papers that have been cited more than 900 times, and has international collaboration with a number of scientific groups.</p> | Professor Kilstrup´s areas of expertise include gene regulation, microbial physiology, and molecular biology, with emphasis on medically and industrial important bacteria as ''Salmonella enterica'', ''Escherichia coli'' and ''Lactococcus lactis'' using both genetic and DNA recombinant techniques. Special expertise is found in the area of stress response and the genetics and physiology of nucleotide metabolism. Current major research project is the analysis of global regulatory networks (stress response) in ''L. lactis'', including physiological studies, proteomics (2D-gel electrophoresis coupled to mass spectrometry), transcriptomics (transcriptional analysis using DNA microarray), and biochemical characterization of regulatory systems. He is the author or co-author of more than 25 scientific papers that have been cited more than 900 times, and has international collaboration with a number of scientific groups.</p> | ||
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<br><h4>Scientific Background</h4> | <br><h4>Scientific Background</h4> | ||
- | <p align="justify">Peter Ruhdal Jensen is professor and leader of the Center for Systems Microbiology at the Institute of Systemsbiology (DTU-BIOSYS). He is educated as a civil engineer in 1988 and he also helds a phD from DTU. He had a post.doc position at the Netherlands Cancer Institute in the Netherlands from 1992 to 1994. He has been associate professor at DTU from 1995 and became professor at DTU in 2006. His areas of research include Systems Biology, Molecular Biology, Genetics and Microbial Physiology. Professor Ruhdal Jensen works with microbiological systems and applies control analysis and modeling to describe complex properties of biological systems. He uses both bacteria and yeast as model systems, with focus on bacteria for industrial production processes. He has been the author or co-author | + | <p align="justify">Peter Ruhdal Jensen is professor and leader of the Center for Systems Microbiology at the Institute of Systemsbiology (DTU-BIOSYS). He is educated as a civil engineer in 1988 and he also helds a phD from DTU. He had a post.doc position at the Netherlands Cancer Institute in the Netherlands from 1992 to 1994. He has been associate professor at DTU from 1995 and became professor at DTU in 2006. His areas of research include Systems Biology, Molecular Biology, Genetics and Microbial Physiology. Professor Ruhdal Jensen works with microbiological systems and applies control analysis and modeling to describe complex properties of biological systems. He uses both bacteria and yeast as model systems, with focus on bacteria for industrial production processes. He has been the author or co-author of more than 80 articles, and has collaborated with a number of research groups around the world.</p></td> |
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<br><h4>Scientific Background</h4> | <br><h4>Scientific Background</h4> | ||
- | + | Sebastien Lemire has a post.doc position at the Center for Systems Micriobiology (CSM) at DTU. He arrived in Denmark in May 2007 after a PhD in the lab of Lionelllo Bossi in Gif-Sur-Yvette, France and 2 years of post-doc in the lab of Tetsuro Yonesaki at Osaka University, Japan. He has also worked in the USA during his masters degree and there the virus for phages infected him and he got interested in the genetics approach to biological questions. He is especially interested in the regulation of lysogeny in Salmonella prophages and how those phages contribute to Salmonella virulence. | |
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Revision as of 12:25, 25 October 2010
Home | The Team | The Project | Parts submitted | Results | Notebook | Blog |
Extras: |
Greetings from Team DTU! The goal of our project is to enable colonies of E. coli bacteria to transition between production of two different reporter proteins. In our system, switching between states will be induced by exposing the bacteria to different inputs. Each of the states will have a specific input associated with it. There are multiple potential applications for biologicals "switches" such as these, this includes the improved control of production of additives in industrial biotechnological processes. For more details, please click here.
The team in Paris for the iGEM workshop (Malte is missing). |
Our Team of Students
Anastasiya S. Haugaard |
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Anja Sander |
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Annemi Ingebrekt Jollmann |
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Grzegorz 'Greg' Slodkowicz |
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Juliet Frederiksen |
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Lisa Blanc Iversen |
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Martin Malthe Borch |
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Maya Friis Kjaergaard |
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Patrick Fortuna |
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Thomas Trolle |
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Our Supervisors
Chris Workman |
Scientific BackgroundChristopher Workman is associate professor at the Center of Biological Sequence Analysis (CBS) at DTU. Dr. Workman has nine years of combined biotech industry and post-graduate experience. This includes three years of postdoctoral training in a leading Systems Biology lab at the University of California, San Diego headed by Dr. Trey Ideker. During this period he led a project that resulted in a map of transcriptional regulatory pathways that control the DNA damage response in yeast and a first author publication in Science. Dr. Workman has developed a number of bioinformatic tools and analysis methods that support research in transcriptional regulation. He has extensive experience analyzing gene expression microarray data from almost all technology platforms. In particular, he has pioneered improved methods of Affymetrix probe-level data analysis and has contributed to the widely used Bioconductor project. He has also contributed as a developer for the Cytoscape open source project. (source: http://www.phenoxigen.eu/index.php?id=3 |
Mogens Kilstrup |
Scientific BackgroundMogens Kilstrup received his master degree in 1986 in biochemistry from the University of Copenhagen as well as his PhD degree in Molecular biology in 1992. After a Post doctoral position at DTU from 1993, he was appointed as associate professor in 2000 and advanced to professor in 2008 at Center for Systems Microbiology (CSM) at DTU. Professor Kilstrup´s areas of expertise include gene regulation, microbial physiology, and molecular biology, with emphasis on medically and industrial important bacteria as ''Salmonella enterica'', ''Escherichia coli'' and ''Lactococcus lactis'' using both genetic and DNA recombinant techniques. Special expertise is found in the area of stress response and the genetics and physiology of nucleotide metabolism. Current major research project is the analysis of global regulatory networks (stress response) in ''L. lactis'', including physiological studies, proteomics (2D-gel electrophoresis coupled to mass spectrometry), transcriptomics (transcriptional analysis using DNA microarray), and biochemical characterization of regulatory systems. He is the author or co-author of more than 25 scientific papers that have been cited more than 900 times, and has international collaboration with a number of scientific groups. |
Peter Ruhdal Jensen |
Scientific BackgroundPeter Ruhdal Jensen is professor and leader of the Center for Systems Microbiology at the Institute of Systemsbiology (DTU-BIOSYS). He is educated as a civil engineer in 1988 and he also helds a phD from DTU. He had a post.doc position at the Netherlands Cancer Institute in the Netherlands from 1992 to 1994. He has been associate professor at DTU from 1995 and became professor at DTU in 2006. His areas of research include Systems Biology, Molecular Biology, Genetics and Microbial Physiology. Professor Ruhdal Jensen works with microbiological systems and applies control analysis and modeling to describe complex properties of biological systems. He uses both bacteria and yeast as model systems, with focus on bacteria for industrial production processes. He has been the author or co-author of more than 80 articles, and has collaborated with a number of research groups around the world. |
Sébastien Lemire |
Scientific BackgroundSebastien Lemire has a post.doc position at the Center for Systems Micriobiology (CSM) at DTU. He arrived in Denmark in May 2007 after a PhD in the lab of Lionelllo Bossi in Gif-Sur-Yvette, France and 2 years of post-doc in the lab of Tetsuro Yonesaki at Osaka University, Japan. He has also worked in the USA during his masters degree and there the virus for phages infected him and he got interested in the genetics approach to biological questions. He is especially interested in the regulation of lysogeny in Salmonella prophages and how those phages contribute to Salmonella virulence. |