Team:ESBS-Strasbourg
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- | + | Preliminary project description : | |
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- | < | + | <p class="MsoNormal" align="left">Inducible systems are used every day in labs, |
+ | but chemical inducers have some limitations :</p> | ||
+ | <p class="MsoNormal" align="left">-Delayed induction (certain time between | ||
+ | adding the chemical and seeing the result)</p> | ||
+ | <p class="MsoNormal" align="left">-Interference with host metabolism</p> | ||
+ | <p class="MsoNormal" align="left">-Only one way induction (once we add the | ||
+ | chemical we cannot remove it)</p> | ||
+ | <p class="MsoNormal" align="left">-Chemicals are expensive</p> | ||
+ | <p class="MsoNormal" align="left">-Not always available</p> | ||
+ | <p class="MsoNormal" align="left"> </p> | ||
+ | <p class="MsoNormal" align="left">The aim of the ESBS-Strasbourg team is to | ||
+ | create a <i>“light <b><span style="color:red">controllable</span></b> specific | ||
+ | protein degradation system”</i>, which will overpass the classical chemical | ||
+ | induction limitations:</p> | ||
+ | <p class="MsoNormal" align="left">-Instant induction (no transcription and | ||
+ | translation needed…)</p> | ||
+ | <p class="MsoNormal" align="left">-No interference with host metabolism</p> | ||
+ | <p class="MsoNormal" align="left">-Controllable (On/Off)</p> | ||
+ | <p class="MsoNormal" align="left">-Cheap</p> | ||
+ | <p class="MsoNormal" align="left">-Always available</p> | ||
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Revision as of 15:33, 25 July 2010
Preliminary project description :
Inducible systems are used every day in labs, but chemical inducers have some limitations :
-Delayed induction (certain time between adding the chemical and seeing the result)
-Interference with host metabolism
-Only one way induction (once we add the chemical we cannot remove it)
-Chemicals are expensive
-Not always available
The aim of the ESBS-Strasbourg team is to create a “light controllable specific protein degradation system”, which will overpass the classical chemical induction limitations:
-Instant induction (no transcription and translation needed…)
-No interference with host metabolism
-Controllable (On/Off)
-Cheap
-Always available
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