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| - | <h1> | + | <h1>About the competetion</h1> |
| - | < | + | <p><span style="font-weight:normal;font-size:130%;">iGEM (international genetically engineered machines competition) is an international competition in synthetic biology, hosted by the MIT in Boston. The aim of this competition is to answer a basic question that Randy Rettberg, the director of iGEM, once described as follows: "Can simple biological systems be built from standard, interchangeable parts and operated in living cells? Or is biology just too complicated to be engineered in this way?" The iGEM-approach to answer that question is to actually try to engineer biological systems with a proper function. To this end, more than 100 interdisciplinary student teams from all over the world, mainly consisting of undergraduate students in biology, biochemistry, engineering, informatics and mathematics, carry out different projects during the Summer. These projects reach from medical applications, i.e. genetically modified bacteria used in cancer-treatment to environmental and manufacturing projects, i.e. the construction of a watch-like counter consisting of living cells. In contrast to classical genetic engineering where only one gene is transferred from organism A to organism B, synthetic biology goes forward into the construction of whole new systems with a completely new function. Therefore, all iGEM-Teams get access to a gene- Database called registry, where hundreds of different genetic parts with characterized functions are available in a "plug-and-play" –like format. These parts can be simply stuck together to build functional systems. The rising number of iGEM-Teams over the last years as well as the upcoming public interest in iGEM, the iGEM-Teams' projects and synthetic biology in general shows, that synthetic biology will for sure have a great impact in many different fields of both scientific research and every-day life.</span><p> |
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Revision as of 07:28, 21 October 2010
Main Page
Concept Anime
About The Project
Mosquito intelligence terminator(MIT)
Monday, 4 October 2010 at 20:30 GMT, by SiteAdmin
The Mosquito Intelligent Terminator (MIT) is designed and optimized to be an ecological and environmental friendly mosquito pesticide. MIT is an engineered E. coli secreting crystal proteins isolated from Bacillus thuringiensis to kill mosquito larvae, or commonly known as wrigglers. These crystal proteins are toxic to certain types of mosquitoes only and are not pathogenic to mammals. We designed a temperature-dependent genetic circuit expressing high levels of crystal proteins at room temperature only, thus production does not occur at incubation temperature. In order to make an environmentally safe insecticide, our design also incorporates a genetic circuit controlling the population size of E. coli, thus a surplus will never exist as E. coli population is self-maintained within the system. This intelligent terminator is not limited to mosquitos only, as the intelligent terminator system can be custom fitted with different cry genes to other insect species. Currently, with more than one hundred crystal proteins targeting various insect species, our design may potentially serve as a promising pest control solution in the future.
Our School
Nation Chiao Tung University
National Chiao Tung University was founded in the suburbs of Shanghai in 1896, sixteen years before the birth of the Republic of China, at the suggestion of Hsuan-Wai Shen, Minister of Foreign Affairs of the Ching Dynasty. The University was first named Nanyang College. It was established to meet the urgent need to introduce western civilization into China. The college initially focused only on politics, law, and translations of western books. In the later years of the Ching Dynasty, the college was renamed the Vocational College of Higher Education and was governed by the Ministry of Post and Transportation. By Including new vocational programs, such as business, electrical engineering, shipping management, and railway management, the college played a major role in science and engineering education in modern Taiwan.
Acknowlegement
The Team Logo
