Team:ETHZ Basel

From 2010.igem.org

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{{ETHZ_Basel10}}
{{ETHZ_Basel10}}
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{{ETHZ_Basel10_Start}}
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{{ETHZ_Basel10_Introduction}}
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= Welcome to the wiki of the ETH Zurich iGEM team =
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= E. lemming - a remotely controlled living robot by ETH Zurich =
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{{ETHZ_Basel10_Teaser}}
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<html>
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<head>
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<style type="text/css">
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#teaser {
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font: 10px normal "Verdana", Helvetica, sans-serif;
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#main {
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float: left;
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border: 1px solid #ccc;
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padding: 5px;
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float: left;
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border-top: 1px solid #fff;
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.image_thumb ul li.hover {
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.image_thumb ul li.active {
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cursor: default;
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html .image_thumb ul li h2 {
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font-size: 12px;
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.image_thumb ul li p{display: none;}
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</style>
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<!--Call jQuery-->
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<script type="text/javascript" src="./jquery-1.3.2.min.js"></script>
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<script type="text/javascript">
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$(document).ready(function() {
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//Show Banner
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$(".main_image .desc").show(); //Show Banner
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$(".main_image .block").animate({ opacity: 0.85 }, 1 ); //Set Opacity
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//Click and Hover events for thumbnail list
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$(".image_thumb ul li:first").addClass('active');
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$(".image_thumb ul li").click(function(){
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//Set Variables
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var imgAlt = $(this).find('img').attr("alt"); //Get Alt Tag of Image
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var imgTitle = $(this).find('a').attr("href"); //Get Main Image URL
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if ($(this).is(".active")) {  //If it's already active, then...
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$(".image_thumb ul li").removeClass('active'); //Remove class of 'active' on all lists
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$(this).removeClass('hover');
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//Toggle Teaser
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$("a.collapse").click(function(){
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$(".main_image .block").slideToggle();
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$("a.collapse").toggleClass("show");
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});
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});//Close Function
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</script>
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</head>
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<div id="teaser">
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<div id="main" class="container">
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<div class="main_image">
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<img src="https://static.igem.org/mediawiki/2010/8/84/ETHZ_Basel_teaser_project.png">
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<div class="desc" style="display: block; ">
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<div class="block" style="display: block; opacity: 0.85; margin-bottom: 0px; ">
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<h2>Project</h2>
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<small>What is E. lemming?</small>
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<p><a href="https://2010.igem.org/Team:ETHZ_Basel/Project">Click here to learn more.</a> </p>
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</div>
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</div>
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</div>
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<div class="image_thumb">
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<ul>
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<li class="">
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<a href="https://static.igem.org/mediawiki/2010/8/84/ETHZ_Basel_teaser_project.png"><img src="https://static.igem.org/mediawiki/2010/b/bd/ETHZ_Basel_teaser_project_thumb.png"></a>
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<div class="block">
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<h2>Project</h2>
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<small>What is E. lemming?</small>
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<p><a href="https://2010.igem.org/Team:ETHZ_Basel/Project">Click here to learn more.</a> </p>
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</div>
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</li>
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<li class="">
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<a href="https://static.igem.org/mediawiki/2010/b/b8/ETHZ_Basel_teaser_molecular_mechanism.png"><img src="https://static.igem.org/mediawiki/2010/7/7a/ETHZ_Basel_teaser_molecular_mechanism_thumb.png"></a>
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<div class="block">
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<h2>Molecular Mechanism</h2>
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<small>How does it work?</small>
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<p><a href="https://2010.igem.org/Team:ETHZ_Basel/Project/Molecular_Mechanism">Click here to learn more.</a> </p>
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</div>
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</li>
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<li class="">
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<a href="https://static.igem.org/mediawiki/2010/d/de/ETHZ_Basel_teaser_info_proc.png"><img src="https://static.igem.org/mediawiki/2010/0/0e/ETHZ_Basel_teaser_info_proc_thumb.png"></a>
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<div class="block">
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<h2>Controlling</h2>
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<small>How is it controlled?</small>
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<p><a href="https://2010.igem.org/Team:ETHZ_Basel/Project/Information_Processing">Click here to learn more.</a> </p>
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</div>
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</li>
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<li class="">
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<a href="https://static.igem.org/mediawiki/2010/3/3f/ETHZ_Basel_teaser_biology.png"><img src="https://static.igem.org/mediawiki/2010/f/f9/ETHZ_Basel_teaser_biology_thumb.png"></a>
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<div class="block">
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<h2>Biology & Wet Laboratory</h2>
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<small>How is it implemented?</small>
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<p><a href="https://2010.igem.org/Team:ETHZ_Basel/Biology">Click here to learn more.</a> </p>
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</div>
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</li>
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<li class="">
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<a href="https://static.igem.org/mediawiki/2010/1/16/ETHZ_Basel_teaser_molecular_models.png"><img src="https://static.igem.org/mediawiki/2010/1/1f/ETHZ_Basel_teaser_molecular_models_thumb.png"></a>
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<div class="block">
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<h2>Molecular Modeling</h2>
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<small>How does modeling help?</small>
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<p><a href="https://2010.igem.org/Team:ETHZ_Basel/Modeling">Click here to learn more.</a> </p>
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</div>
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</li>
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<li class="">
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<a href="https://static.igem.org/mediawiki/2010/2/21/ETHZ_Basel_teaser_information_processing.png"><img src="https://static.igem.org/mediawiki/2010/5/52/ETHZ_Basel_teaser_information_processing_thumb.png"></a>
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<div class="block">
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<h2>Information Processing</h2>
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<small>How is it controlled in detail?</small>
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<p><a href="https://2010.igem.org/Team:ETHZ_Basel/InformationProcessing">Click here to learn more.</a> </p>
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</div>
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</li>
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</ul>
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</div>
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</div>
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</div>
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</html>
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The core idea of our project is to control chemotaxis of ''E. coli'' by means of light! We'll realize this by hijacking and perturbing the tumbling / directed flagellar movement apparatus. By coupling directed flagellar movement regulating proteins to a '''novel synthetic light-sensitive spatial localization system''', their activity can be controlled reversibly. A light-sensitive dimerizing complex fused to this regulating proteins at a spatially fixed location is induced by light pulses and therefore localization of the two molecules can be manipulated.  Tumbling / directed flagellar movement rates are monitored by image processing algorithms, which are linked to the light-pulse generator. This means that ''E. coli'' tumbling is induced or suppressed simply by pressing a light switch! This synthetic network enables control of single E. coli cells: '''We'll make them move like mindless "Lemmings"''' in the direction they are forced to go!
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== Sponsors ==
== Sponsors ==
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[[Image:ETHZ_Basel_sponsors.jpg|none|center|800px|]]
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{| border="0" align="center"
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|<html><img src="https://static.igem.org/mediawiki/2010/6/65/ETHZ_Basel_sponsors.jpg"></html>
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|}

Latest revision as of 01:34, 16 November 2010

E. lemming - a remotely controlled living robot by ETH Zurich

  • Motivation & Project Idea

    What is E. lemming?

  • E. lemming - The Movie

    Watch a short animation!

  • Biology & Wet Laboratory

    How is it implemented?

  • Mathematical Modeling

    How does modeling help?

  • Information Processing

    How is it controlled?

  • Achievements

    What was achieved?

  • Team

    Who is behind E. lemming?

Sponsors

Retrieved from "http://2010.igem.org/Team:ETHZ_Basel"