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Team:UCSF/Home
From 2010.igem.org
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{{Template:UCSF/Head}} | {{Template:UCSF/Head}} | ||
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<html> | <html> | ||
<body> | <body> | ||
| + | <style> | ||
| + | #TOC {width:180px; border:1px solid #333; border-top:none} | ||
| + | .TOC {width:180px; font:12px Verdana,Arial; color:#333} | ||
| + | .TOC dt {width:168px; padding:4px 6px; font-weight:bold; cursor:pointer; background-color:#666; background-image:url(http://sandbox.leigeber.com/accordion/images/arrow_down.gif); background-position:right center; background-repeat:no-repeat; color:#fff; border-top:1px solid #333} | ||
| + | .TOC dt:hover {background-color:#555} | ||
| + | .TOC .open {background-color:#444; background-image:url(http://sandbox.leigeber.com/accordion/images/arrow_up.gif)} | ||
| + | .TOC dd {overflow:hidden; background:white;position:relative;left:-24px; width:180px} | ||
| + | .TOC span {display:block; width:170; border-top:none; padding:5px} | ||
| + | </style> | ||
| + | <script src="http://sandbox.leigeber.com/accordion/script.js"></script> | ||
<table border="0" cellpadding="0" cellspacing="0" style="position:relative; top:-10px"> | <table border="0" cellpadding="0" cellspacing="0" style="position:relative; top:-10px"> | ||
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| - | <table width="965" border="0" cellpadding="0" cellspacing="0 | + | <table width="965" border="0" cellpadding="0" cellspacing="0"> |
<tr> | <tr> | ||
| - | <td width="180"> | + | <td width="180" valign="top"> |
| + | <div style="background-color:white; height:1000px"> | ||
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| + | <div id="TOC"> | ||
| + | <dl class="TOC" id="slider"> | ||
| + | <dt>About</dt> | ||
| + | <dd> | ||
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| + | <span>This lightweight (1.2 KB) JavaScript accordion can easily be customized to integrate with any website. For more information visit <a href="http://www.leigeber.com">leigeber.com</a>/</span> | ||
| + | </dd> | ||
| + | <dt>Instructions</dt> | ||
| + | <dd> | ||
| + | <span>To initialize an accordion use the following code:<br /><br /> | ||
| + | <code> | ||
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| + | var mySlider=new accordion.slider("mySlider"); | ||
| + | <br />mySlider.init("slider",0,"open"); | ||
| + | </code><br /><br /> | ||
| + | The init function takes 3 parameters: the id of the "dl", the location of the initially expanded section (optional) and the class for the active header (optional). | ||
| + | </span> | ||
| + | </dd> | ||
| + | <dt>Licensing & Support</dt> | ||
| + | <dd> | ||
| + | <span>This script is provided as-is with no warranty or guarantee. It is available at no cost for any project, non-commercial or commercial. Paid support is available by <a href="http://www.leigeber.com/contact/">clicking here</a>.</span> | ||
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| + | </dd> | ||
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| + | </div> | ||
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</td> | </td> | ||
| - | <td width="779"><div style="background-color:#E4FEE0; height:1000px"></div></td> | + | <td width="779" valign="top"><div style="background-color:#E4FEE0;height:1000px"></div></td> |
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| + | <script type="text/javascript"> | ||
| + | var slider=new accordion.slider("slider"); | ||
| + | slider.init("slider",0,"open"); | ||
| + | </script> | ||
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</body> | </body> | ||
</html> | </html> | ||
Latest revision as of 20:46, 7 September 2010
Project Description
Natural killer (NK) cells of the immune system identify cancer and virally-infected cells and kill them. These potent killers travel throughout the body, recognizing proteins and other molecules on the surface of cells. In order to differentiate between healthy and diseased cells, NK cells use a variety of receptors, which bind to specific ligands at the target cells’ surface. The balance between activating and inhibitory signals will tell the NK cell if the target cell is diseased or healthy, respectively. If the target cell is deemed potentially dangerous, the NK cell grips the target cell tightly and creates an immunological synapse at the site of adhesion. Within this immunological synapse, the NK cell releases cytotoxic granules to kill the target cell without harming any nearby cells allowing for a direct, apoptotic death.
Our team will focus on improving NK cells’ specificity and killing efficiency towards certain cancer types. By using synthetic biology tools and logic gates’ design, we hope to create powerful killing biomachines for the fight against cancer. Our newly engineered synthetic devices would have the potential to enhance current adoptive cell-based immunotherapy for cancer patients.
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