Round 1: Group Brainstorming Session
Health/Medicine
Release in presence of wound signal (pH) Factor VIII
Symbiosis with human body
Selective phagocytosis (absorb toxin)
Selective phagocytosis (lead)
Phagocytosis for drug overdoses
Drug sensing bactera
Bacterial spermicide
Drug delivery method through WBC
Apoptosis with drug delivery when disease is recognized
Vitamin and mineral delivery
Bacteria that takes up excess ions in the body
Self Healing material: growth factor
Apoptosis in presence of a particular disease
Swine Flu testing on site
Target bad cells selectively based on offset in circadian rythmn
Cure celiac’s with bacteria
Ethrypoeitin production in e. coli
Thrombolytics in presence in LDL
Thrombolytics in precense of clots (macrophages)
Bacterial pacemakers
Food/Energy
Supplementary vitamin and minerals to be grown on produce
Removable pesticide bacterial film
Cheese reservatrol
Splitting Hydrogen from water
Electrogenesis: produce voltage from bacteria
Environment
Consume gases in the air (ozone)
Consume (CFCs)
On site radiation testing (make it click like a Geiger counter)
Breaking down plastics (look at past presentation)
Photo-driven battery
Manufacturing/Industrial
Trace explosive Bacteria
EXPLODING BACTERIA
Bacterial Superglue
Resistors
Capacitors (Storing charge)
Phagocytosis for water in shoes
Bacterial barometer
Bacterial paper to print on
Active pH buffer for e. coli (target pH)
pH meter
Cilia creating fluid flow, generating fluid current
Create ferrofluuid to create magnetism
Bacteria to regulate the temperature of a surface (endothermic and exothermic reaction)
Long lasting bacterial sunblock
Bacterial Clothing
Thermal heating for toes
Adjusting Young’s Modulus
Contracting group of cells
Thermometer
Bacterial film that responds to laser so you can sketch on it. (express GFP light induced promoter)
Bacterial Gears
Miscellaneous
ELISA for DNA
ELISA for mRNA
Magnetic Bacteria
Faster biodegradation (Signal activated ) (isn't this environmental?)
Oncoprotein expressed on the outside missing ligand binding portion
Cytoskeleton in bacteria
Engineering current flow intracellularly
Bacterial gyroscope
Bacterias that produce primers
Proteosome into e. coli design system to keep at steady state to keep e. coli alive
Nail polish (grow back or fade away)
Tight junctions into bacteria
Synthetic Apoptotic signal (and isn't this medical?)
Music Playing Bacteria: loudspeaker
Clock using bacterial gears
Non Newtonian fluid bacteria (using force)
Bacteria piston using sinking and floating mechanism
Gap junction music playing
Rotifers: surviving without water mechanism (protein protection)
Engineering signal glycoproteins into bacteria (integration of virus disrupts reporter gene)
Round 2: Official 2010 iGEM Draft
Each member chose 3 favorite topics to research
Sean - Opsin, Electrogenesis, Tight Junction
Avi - Proteosome, Storing Charge, Magnetic Field
Ben - Pacemaker, Factor8, Excess Ion uptake
Matt - Self Healing Material, WBC, Bacterial Thermometer
Timi - Splitting Water, Primer Production, Oncoprotein Express
Jeremy - Circadian Rhythm, pH meter, Cytoskeleton
Ragan - Selective Phagocytosis, Erythropoietin Production, Inducible Apoptosis
Round 3: Presentation and Voting
Voted on the basis of: Sexiness, Available Parts, Feasibility, and Applications
Narrowed Down to: Cytoskeleton, Magnetic Bacteria, and Self Healing Armor
Round 4: Group Discussion
Cytoskeleton Discarded
Self-Healing Armor altered to Bacterial Skin
B-Cell/T-Cell Response Modeling Introduced
Magnetic Bacteria relegated to side project
Round 5: Presentation and Final Voting
Main Project: Bacterial Skin
Side Project: Magnetic Bacteria (Magnetite Synthesis)
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