Team:UT-Tokyo

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<h2>About Us</h2>
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We are now tackling on three projects; Allergy, Sudoku and Bioaccumulation.
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In the Allergy project, we plan to modify E.coli to be used as an allergy cure by applying hyposensitization therapy.  
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The Sudoku project is designed to solve the popular mathematical puzzle Sudoku by using "intellectualized E.coli".  
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In the Bioaccumulation project, our C.elegans will collect a substance.
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      <li><a href="https://2010.igem.org/Team:UT-Tokyo" id="home">home</a></li>
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      <li><a href="https://2010.igem.org/Team:UT-Tokyo/Team" id="project">team</a></li>
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      <li><a href="https://2010.igem.org/Team:UT-Tokyo/Project" id="team">project</a></li>
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      <li><a href="https://2010.igem.org/Team:UT-Tokyo/Online" id="online">online</a></li>
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      <li><a href="https://2010.igem.org/Team:UT-Tokyo/Contact" id="contact">contact</a></li>
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    We are now tackling on three projects; Allergy, Sudoku and Bioaccumulation. In the Allergy project, we plan to modify <i>E.coli</i> to be used as an allergy cure by applying hyposensitization therapy. The Sudoku project is designed to solve the popular mathematical puzzle Sudoku by using "intellectualized <i>E.coli</i>". In the Bioaccumulation project, our <i>C.elegans</i> will collect a substance.  
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    <h2>Allergy</h2>
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A lot of people are suffering from allergy every year. People sneeze and have trouble in stuffy nose because of house dust or pollen etc. Here, we mainly focus on the pollen allergy that is causing serious problems in many countries.
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To tackle on this problem, we use hyposensitization therapy which makes our body accustom to antigens by intaking them little by little every day. Our <i>E.coli</i> will constantly produce epitopes in our intestines, and the epitopes will be recognized by antibody.
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<h2>About our project</h2>
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Here, we use epitopes of cedar pollen, but this method can be used in other types of allergy and we hope this method will be useful to cure allergy fundamentally.
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&nbsp;<br />
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  <h2>Sudoku</h2>
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<img src="https://static.igem.org/mediawiki/2010/8/85/Sudoku_logo2.png" />
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Sudoku is a logical game to fill numbers from 1 to 9 inside the 9x9 boxes. The rule is simple: Each number should be used once in the same row, column, and 3x3 block.  In this experiment E.coli having information about the boxes will interact with other E.coli, and by applying a certain selection rule they decide the right numbers.  This process is a kind of parallel computation and it mimics differentiation in development.
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&nbsp;&nbsp;&nbsp;&nbsp;Sudoku is a logical game to fill numbers from 1 to 9 inside the 9x9 boxes. The rule is simple: Each number should be used once in the same row, column, and 3x3 block.<br />
 
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&nbsp;&nbsp;&nbsp;&nbsp;In this experiment <i>E.coli</i> having information about the boxes will interact with other yeasts, and by applying a certain selection rule they decide the right numbers.<br />
 
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&nbsp;&nbsp;&nbsp;&nbsp;This process is a kind of parallel computation and it mimics differentiation in development.
 
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  <h2>Bioaccumulation</h2>
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<img src="https://static.igem.org/mediawiki/2010/b/b2/Allergy_logo2.png" /><br />
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A lot of people are suffering from allergy.　Here, we mainly focus on the pollen allergy that is causing serious problems in many countries. To tackle on this problem, we use hyposensitization therapy which makes our body accustom to antigens by intaking them little by little every day. Our E.coli will constantly produce epitopes in our intestines, and the epitopes will be recognized by antibody. This method can be used in other types of allergy and we hope this method will be useful to cure allergy fundamentally.
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&nbsp;&nbsp;&nbsp;&nbsp;Hazardous substances in the soil often become a major problem, especially in the site of factories. The turmoil about transfer of Tsukiji market is fresh in our memory recently. In the present state of affairs, however, there is no effective way to remove hazardous substances in the soil and we must invest a large amount of cost to replace the soil.<br />
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&nbsp;&nbsp;&nbsp;&nbsp;We suggest a project, collecting hazardous substances by using “<i>E.coli</i> in the soil” and ”<i>C.elegans</i>”. Bio accumulation is done through the process; <i>C.elegans</i> preys on <i>E.coli</i> which collected hazardous substances. <i>C.elegans</i> is controlled its behavior and led to the ground the moment preying on <i>E.coli</i>. We can see <i>C.elegans</i> with the naked eye, and the fact makes the collecting of hazardous substances easy. Differing from chemical soil purification, this process can greatly reduce the damage to environment. This conception will become more and more important. <br />
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Bioaccumulation refers to uptake and accumulation of a substance inside the bodies of living things. In this project, there are twice accumulation. First, E.coli absorbs some sources. Second, C.elegans eats that E.coli, then C.elegans whose gene is manipulated changes action to correct easily. As a result, we can collect substances more efficiently.
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Revision as of 19:03, 19 September 2010

UT-Tokyo

About Us

We are now tackling on three projects; Allergy, Sudoku and Bioaccumulation. In the Allergy project, we plan to modify E.coli to be used as an allergy cure by applying hyposensitization therapy. The Sudoku project is designed to solve the popular mathematical puzzle Sudoku by using "intellectualized E.coli". In the Bioaccumulation project, our C.elegans will collect a substance.

About our project

Sudoku is a logical game to fill numbers from 1 to 9 inside the 9x9 boxes. The rule is simple: Each number should be used once in the same row, column, and 3x3 block. In this experiment E.coli having information about the boxes will interact with other E.coli, and by applying a certain selection rule they decide the right numbers. This process is a kind of parallel computation and it mimics differentiation in development.


A lot of people are suffering from allergy.　Here, we mainly focus on the pollen allergy that is causing serious problems in many countries. To tackle on this problem, we use hyposensitization therapy which makes our body accustom to antigens by intaking them little by little every day. Our E.coli will constantly produce epitopes in our intestines, and the epitopes will be recognized by antibody. This method can be used in other types of allergy and we hope this method will be useful to cure allergy fundamentally.


Bioaccumulation refers to uptake and accumulation of a substance inside the bodies of living things. In this project, there are twice accumulation. First, E.coli absorbs some sources. Second, C.elegans eats that E.coli, then C.elegans whose gene is manipulated changes action to correct easily. As a result, we can collect substances more efficiently.

Retrieved from "http://2010.igem.org/Team:UT-Tokyo"