Team:Michigan/Modeling
From 2010.igem.org
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We are developing a mathematical model which describes the degradation of naphthenic acids (NAs) by ''Pseudomonas putida'' and ''Pseudomonas fluorescens'' in a biofilm in a drip flow reactor. We will use the plug flow model to describe the continuous flow of NAs inside the reactor. | We are developing a mathematical model which describes the degradation of naphthenic acids (NAs) by ''Pseudomonas putida'' and ''Pseudomonas fluorescens'' in a biofilm in a drip flow reactor. We will use the plug flow model to describe the continuous flow of NAs inside the reactor. | ||
- | It is known that ''P. putida'' and ''P. fluorescens'' synergistically degrade NAs [4]. The mechanism of the synergistic degradation and differentiation between the two species should have little effect in evaluating the efficiency of NA degradation, thus our models will assume a homogeneous mixture of ''P. putida'' and ''P. fluorescens'' and represent the two species as one organism. | + | In developing the mathematical model, the following assumptions were made: |
+ | (1) It is known that ''P. putida'' and ''P. fluorescens'' synergistically degrade NAs [4]. The mechanism of the synergistic degradation and differentiation between the two species should have little effect in evaluating the efficiency of NA degradation, thus our models will assume a homogeneous mixture of ''P. putida'' and ''P. fluorescens'' and represent the two species as one organism. | ||
+ | (2) We will assume that the microbial population is in a steady state condition, with a balanced growth rate and death rate. | ||
[https://2009.igem.org/Team:uOttawa/Modeling uOttawa] used plug flow to describe nutrient flow in the intestines. | [https://2009.igem.org/Team:uOttawa/Modeling uOttawa] used plug flow to describe nutrient flow in the intestines. |
Revision as of 22:53, 27 August 2010