Team:Stockholm/Modelling/Model
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=== Yildirim N et al model === | === Yildirim N et al model === | ||
- | In a series of 5 equations, They proposed dynamics for mRNA production, <VAR>β</VAR>-galactosidase production, | + | In a series of 5 equations, They proposed dynamics for mRNA production, <VAR>β</VAR>-galactosidase production, allolactose, lactose for Lac operon. In their model they also considered transcriptional and translational delays (ie. <VAR>β</VAR>-galactosidase and <VAR>β</VAR>-galactoside permease production from mRNA is not instant and takes time). |
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- | This model can be simplified. Ahmadzadeh et al. 2005 proposed a simplified model of [http://www.ncbi.nlm.nih.gov/pubmed/12719218 Yildirim N et al 2002], where they ignored time delays for transcription and translation. For more simplification they also assumed that β-galactosidase and β-galactoside permease reach their steady state values instantly, ending up with 3 equations just for mRNA, | + | This model can be simplified. Ahmadzadeh et al. 2005 proposed a simplified model of [http://www.ncbi.nlm.nih.gov/pubmed/12719218 Yildirim N et al 2002], where they ignored time delays for transcription and translation. For more simplification they also assumed that β-galactosidase and β-galactoside permease reach their steady state values instantly, ending up with 3 equations just for mRNA, lactose and allolactose dynamics. Full description of the assumptions behind this simplification can be found at Ahmadzadeh et al. 2005 . |
- | [[image:Su_team_simplified_equation_sets.png| | + | [[image:Su_team_simplified_equation_sets.png|580px]] |
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{{Stockholm/Footer}} | {{Stockholm/Footer}} |
Latest revision as of 02:19, 28 October 2010
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