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Team:Cambridge/Bioluminescence/Vibrio Modelling
From 2010.igem.org
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{{:Team:Cambridge/Templates/headerbar|colour=#386abc|title=Project Vibrio: Modelling}} | {{:Team:Cambridge/Templates/headerbar|colour=#386abc|title=Project Vibrio: Modelling}} | ||
| - | We constructed a '''mathematical model''' of the Vibrio lux system. Unfortunately we were not able to characterise the individual genes, luxC, luxD, luxE, luxA and luxB, well enough to gain the kinetic data needed to model this system. | + | We constructed a '''mathematical model''' of the Vibrio lux system. Unfortunately we were not able to characterise the individual genes, luxC, luxD, luxE, luxA and luxB, well enough to gain the kinetic data needed to model this system. Therefore we do not have as detailed a model as we did for the [https://2010.igem.org/Team:Cambridge/Bioluminescence/Firefly_Modelling firefly system] Nevertheless here is a diagrammatic representation of our model, generated from SBML using [http://sbw.kgi.edu/Layout/Default.aspx the SBW layout tool]. |
| - | [[Image:Cambridge-Vibrio-model.png |700px]] | + | |
| + | [[Image:Cambridge-Vibrio-model.png |700px|]] | ||
==The literature== | ==The literature== | ||
[http://www.ncbi.nlm.nih.gov/pubmed/19081933 Welham and Stekel (2009)] developed a mathematical model of the ''Xenorhabdus luminescens'' system. The organisation and function of the lux genes in this organism is very comparible to those of ''V. fischeri''. | [http://www.ncbi.nlm.nih.gov/pubmed/19081933 Welham and Stekel (2009)] developed a mathematical model of the ''Xenorhabdus luminescens'' system. The organisation and function of the lux genes in this organism is very comparible to those of ''V. fischeri''. | ||
{{:Team:Cambridge/Templates/footer}} | {{:Team:Cambridge/Templates/footer}} | ||
Latest revision as of 18:02, 27 October 2010
Project Vibrio: Modelling
We constructed a mathematical model of the Vibrio lux system. Unfortunately we were not able to characterise the individual genes, luxC, luxD, luxE, luxA and luxB, well enough to gain the kinetic data needed to model this system. Therefore we do not have as detailed a model as we did for the firefly system Nevertheless here is a diagrammatic representation of our model, generated from SBML using [http://sbw.kgi.edu/Layout/Default.aspx the SBW layout tool].
The literature
[http://www.ncbi.nlm.nih.gov/pubmed/19081933 Welham and Stekel (2009)] developed a mathematical model of the Xenorhabdus luminescens system. The organisation and function of the lux genes in this organism is very comparible to those of V. fischeri.
