Team:KAIST-Korea/Project
From 2010.igem.org
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<span style =font-size:18px><b><center>TB diagnosing yeast; we aim to discover the yeast that will make a difference in the world.</center></b></span> | <span style =font-size:18px><b><center>TB diagnosing yeast; we aim to discover the yeast that will make a difference in the world.</center></b></span> | ||
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We have developed simple and effective tuberculosis antigen detecting method using modified antibody in yeast. Our project is based on FGFR-STAT1 pathway in human. We added fusion antibody and GFP to display existence of antigen. In other words, this yeast emits light when antigen is attached. Tuberculosis, one of the deadliest diseases, has taken many lives since antiquity. Although cases of tuberculosis are rarely reported in a developed country, it still is prevalent in a developing country. Therefore, accurate and rapid tuberculosis diagnosis method has been always required. | We have developed simple and effective tuberculosis antigen detecting method using modified antibody in yeast. Our project is based on FGFR-STAT1 pathway in human. We added fusion antibody and GFP to display existence of antigen. In other words, this yeast emits light when antigen is attached. Tuberculosis, one of the deadliest diseases, has taken many lives since antiquity. Although cases of tuberculosis are rarely reported in a developed country, it still is prevalent in a developing country. Therefore, accurate and rapid tuberculosis diagnosis method has been always required. | ||
Our diagnostic method can be modified, by changing antibody, for cases of other diseases such as malaria, HIV or cancer. We strongly believe that our project will offer a new way of diagnosis contributing to the eradication of pandemics. | Our diagnostic method can be modified, by changing antibody, for cases of other diseases such as malaria, HIV or cancer. We strongly believe that our project will offer a new way of diagnosis contributing to the eradication of pandemics. | ||
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<center><embed src="https://static.igem.org/mediawiki/2010/6/6e/Whole_pathway_final.swf" width=550 height=400></embed></center> | <center><embed src="https://static.igem.org/mediawiki/2010/6/6e/Whole_pathway_final.swf" width=550 height=400></embed></center> |
Latest revision as of 08:14, 20 October 2010
DiscoverY [disˈkəvər wī]
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