Team:ETHZ Basel/InformationProcessing
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Although the synthetic network we implemented makes the tumbling frequency of an E. coli cells dependent on red and far-red light, the biological part alone is not sufficient to control the swimming direction of the E. lemming. Thus, it is complemented by an in-silico network realizing a controller which automatically sends the light signals and, by thus time-dependently changing the tumbling frequency, forces the cell to swim in a desired direction. The interface between the two sub-networks, the genetic network and the in-silico network, is defined as the current microscope image (in-vivo -> in-silico) and the red and far-red light signals (in-silico -> in-vivo). By interconnecting both sub-networks, we thus can close the loop and obtain the overall network, which allows us to increase the information processing capabilities significantly compared to traditional synthetic networks completely realized in-vivo. | Although the synthetic network we implemented makes the tumbling frequency of an E. coli cells dependent on red and far-red light, the biological part alone is not sufficient to control the swimming direction of the E. lemming. Thus, it is complemented by an in-silico network realizing a controller which automatically sends the light signals and, by thus time-dependently changing the tumbling frequency, forces the cell to swim in a desired direction. The interface between the two sub-networks, the genetic network and the in-silico network, is defined as the current microscope image (in-vivo -> in-silico) and the red and far-red light signals (in-silico -> in-vivo). By interconnecting both sub-networks, we thus can close the loop and obtain the overall network, which allows us to increase the information processing capabilities significantly compared to traditional synthetic networks completely realized in-vivo. | ||
- | In this section we will describe in detail the in-silico part of the network. For the in-vivo part, we refer to [[Team:ETHZ_Basel/Biology]] | + | In this section we will describe in detail the in-silico part of the network. For the in-vivo part, we refer to the [[Team:ETHZ_Basel/Biology | Biology & Wet Laboratory]] section. |
Revision as of 18:16, 14 October 2010
Information Processing Overview
In this section we will describe in detail the in-silico part of the network. For the in-vivo part, we refer to the Biology & Wet Laboratory section.