Team:Virginia United/Team

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Quorum Sensing Amplifiers and a Codesign Approach for Information Processing
Quorum Sensing Amplifiers and a Codesign Approach for Information Processing
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Synthetic biology endeavors to create information processing systems modeled on digital electronics.  The use of quorum sensing can help transform an inherently analog molecular signal into a binary response and simultaneously allow the tuning of input response thresholds and signal amplification.  This project demonstrates these capabilities through experimentation and modeling.  Another candidate for reapplying an electronic engineering technique is the codesign of hardware and software to implement a function.  In synthetic biology, codesign might mean implementing a design spec in different expression control regimes and comparing their relative merits.  Our work examines the codesign concept by constructing an AND gate in three different design domains.  We explore the application of these ideas with an environmental sensor.  A unique aspect of our project is the collaborative nature involving five institutions at three locations, which fostered a codesign-like approach using three distinct assembly techniques.
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Synthetic biology endeavors to create information processing systems modeled on digital electronics.  The use of quorum sensing can help transform an inherently analog molecular signal into a binary response and simultaneously allow the tuning of input response thresholds and signal amplification.  This project demonstrates these capabilities through experimentation and modeling.  Another candidate for reapplying an electronic engineering technique is the codesign of hardware and software to implement a function.  In synthetic biology, codesign might mean implementing a design specification in different expression control regimes and comparing their relative merits.  Our work examines the codesign concept by constructing an AND gate in three different design domains.  We explore the application of these ideas with an environmental sensor.  A unique aspect of our project is the collaborative nature involving five institutions at three locations, which fostered a codesign-like approach using three distinct assembly techniques.
== '''Where we're from''' ==
== '''Where we're from''' ==

Revision as of 00:51, 26 October 2010

igem

Virginia United 3.jpg

Who we are

Advisors:

  • Instructor 1: Jean Peccoud
  • Instructor 2: Martha Eborall
  • Grad Student 1: George McArthur
  • Grad Student 2: Matt Lux
  • Advisor 1 : Daniel Tarjan
  • Advisor 2 : Erik Fernandez
  • Advisor 3 : Stephen Fong
  • Advisor 4 : Brian Sayre
  • Advisor 5 : Ryan Senger
  • Advisor 6 : Keith Kozminski
  • Advisor 7 : Jason Papin
  • Advisor 8 : Inchan Kwon

Undergrads:

  • Student 1: Rohini Manaktala
  • Student 2: Yong Wu
  • Student 3: Megan Barron
  • Student 4: Arjun Athreya
  • Student 5: Austin Chamberlin
  • Student 6: Sara Brickman
  • Student 7: Adam Bower
  • Student 8: Brett Tolliver
  • Student 9: Daniel Chique
  • Student 10: Dasha Nesterova
  • Student 11: Jane Carter
  • Student 12: Joe Edwards
  • Student 13: Karis Childs
  • Student 14: Priscilla Maame Yaa Agyemang
  • Student 15: Maria McClintock

What we did

Quorum Sensing Amplifiers and a Codesign Approach for Information Processing

Synthetic biology endeavors to create information processing systems modeled on digital electronics. The use of quorum sensing can help transform an inherently analog molecular signal into a binary response and simultaneously allow the tuning of input response thresholds and signal amplification. This project demonstrates these capabilities through experimentation and modeling. Another candidate for reapplying an electronic engineering technique is the codesign of hardware and software to implement a function. In synthetic biology, codesign might mean implementing a design specification in different expression control regimes and comparing their relative merits. Our work examines the codesign concept by constructing an AND gate in three different design domains. We explore the application of these ideas with an environmental sensor. A unique aspect of our project is the collaborative nature involving five institutions at three locations, which fostered a codesign-like approach using three distinct assembly techniques.

Where we're from

Virginia United is a regional team between Virginia Tech, University of Virginia, Virginia Commonwealth University, Bluefield State College, and Virginia State University. The team members spent their summer spread between labs at Virginia Tech, University of Virginia, and Virginia Commonwealth University working towards a common project.

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