Team:USTC/Modeling/a

Known Conditions

This table illustrate some basic information of pdu shell protein family.[1]

Table 1| Basic information of pdu shell protein family.

Figure 1| 3-dimension structure of the known shell proteins from Salmonella enterica . UPPER: pduU. [2] MIDDLE: pduA. [3] DOWN：pduT. [3]

Hypothesis

I）Pdu N is the vertex and its pentametic structures

for its identity with a proved vertex pentametic protein---CcmL. [4]

Figure 2| A diagram showing the construction of a large icosahedron from many smaller hexagons and 12 pentagons at the vertices. The figure shown has a triangulation number (T) of 75 (29). [4]

II) Hexamers forms the facets, which comprises the building blocks of bacterial microcompartment shells

Results

Conclusion

Reference

[1] Martin J. Warren, et al. 2010. Synthesis of empty bacterial microcompartments, directed organelle protein incorporation, and evidence of filament-associated organelle movement. Molecular Cell. 2010 Apr 38 (2), 305–315

[2] Structure of the PduU shell protein from the Pdu microcompartment of Salmonella. Structure. 2008 Sep 16(9):1324-32

[3] Structural insights into the mechanisms of transport across the Salmonella enterica Pdu microcompartment shell. J Biol Chem. 2010 Sep: [Epub ahead of print]

[4] Atomic-level models of the bacterial carboxysome shell. Science. 2008 Feb, 319(5866):1083-6