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Early on, we decided to create a computational model of our pattern generation system. This would allow us to accomplish several important goals:
- Demonstrate that the circuit logic was sound
- Test the viability of our construct given realistic parameters
- Probe the effects that different parameters would have on the system
- Identify potential failure modes, and the events that might trigger them
- Evaluate alternative designs of the construct
With these goals in mind, we set about formalizing the system.
To start, we generate equations for all of the transcription reactions:
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We would like to take a moment to thank all of our sponsors for their very generous donations, as we could not have done this without your help!
We would also like to thank and acknowledge:
Our Advisors
Marc Facciotti
Ilias Tagkopoulos
Technical Guidance
David Larsen
Andrew Yao
Visiting iGEMer
Jia Li of Zhejiang University (TEAM ZJU-China)
cI Promoter Screen
Drew Endy - Stanford
Thomas Schneider - NIH
Want to sponsor us? Send an email to mtfacciotti@ucdavis.edu to discuss various ways you can help! :)
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