Team:SDU-Denmark/project-m

From 2010.igem.org

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(3. Description of model)
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=== 4. Flagella dynamics ===
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=== Flagella dynamics ===
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The next thing to be considered was how the flagella dependent on the fluid flow, ie. if we place a bacterium at an angle θ with the wall will it remain at that angle or will it get pulled around by the flow in the pipe, thus changing its position. The two extreme situations would be either that the flagella stick very hard to the surface and therefor is unaffected by the flow or that it is stick very gently to the surface and depent completely on the flow. In order to create an intermediate situation, we could constrain each flagellum with a harmonic potential, pulling it toward a favored angle(connected to the initial orientation of the fagella when stick to the surface). We believe the answer lies somewhere in between the two extremes, but that doesn't mean the extremes can't tell us anything. We therefore decided to create a model in which the flagella keep still, and one where they are affected by the flow and a potential. The size of the potential can always be set to zero if we want to study the flagella without it.
The next thing to be considered was how the flagella dependent on the fluid flow, ie. if we place a bacterium at an angle θ with the wall will it remain at that angle or will it get pulled around by the flow in the pipe, thus changing its position. The two extreme situations would be either that the flagella stick very hard to the surface and therefor is unaffected by the flow or that it is stick very gently to the surface and depent completely on the flow. In order to create an intermediate situation, we could constrain each flagellum with a harmonic potential, pulling it toward a favored angle(connected to the initial orientation of the fagella when stick to the surface). We believe the answer lies somewhere in between the two extremes, but that doesn't mean the extremes can't tell us anything. We therefore decided to create a model in which the flagella keep still, and one where they are affected by the flow and a potential. The size of the potential can always be set to zero if we want to study the flagella without it.

Revision as of 14:41, 24 October 2010