Team:Purdue/Oxygen Sequestration Brainstorming & Thoughts

From 2010.igem.org

Revision as of 04:03, 29 May 2010 by Tmiller (Talk | contribs)

Check Out & Other Info

This video seems like a good review/introduction to the Calvin cycle.

Quick fix: "Hypoxia" means a lack of oxygen, not an excess. We'll need to find a new transcription factor or find a way to "invert" this one.

Note from Professor Rickus

Okay. So I am pretty out of my element with plants. That is OK!! But it means you are going to need to add some plant experts to your advisors. Don't forget about Dr. Evans and friends at Dow Agro.


Some of you are also looking to how you could link this with cancer. Sean and Aaron are a Cancer DURIs for example. Sung has a basic interest. etc etc.


So I am actually thinking that there is A LOT you could do using this O2 sensitive transcription circuit in cancer! One thing cancer cells are really good at is surviving and adapting to hypoxic environments. In addition, the human cancer stem cells we have in the lab have been shown to be sensitive to their oxygen environments.


I think there is potential in oxygen sensitive transcription.



Add your thoughts below

insert brainstorming ideas within these, initial and date (?)