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Round 1: Group Brainstorming Session


   32)  Release in presence of wound signal (pH) Factor VIII
   33)  Symbiosis with human body
   34)  Selective phagocytosis (absorb toxin)
   35)  Selective phagocytosis (lead)
   36)  Phagocytosis for drug overdoses
   67)  Drug sensing bactera
   69)  Bacterial spermicide        
   24)  Drug delivery method through WBC
   25)  Apoptosis with drug delivery when disease is recognized
   26)  Vitamin and mineral delivery
   62)  Bacteria that takes up excess ions in the body
   5)   Self Healing material: growth factor
   7)   Apoptosis in presence of a particular disease
   16)  Swine Flu testing on site
   37)  Target bad cells selectively based on offset in circadian rythmn
   39)  Cure celiac’s with bacteria
   40)  Ethrypoeitin production in e. coli
   41)  Thrombolytics in presence in LDL
   42)  Thrombolytics in precense of clots (macrophages)
   43)  Bacterial pacemakers


   30)  Supplementary vitamin and minerals to be grown on produce
   31)  Removable pesticide bacterial film
   70)  Cheese reservatrol
   21)  Splitting Hydrogen from water
   18)  Electrogenesis: produce voltage from bacteria


   28)  Consume gases in the air (ozone)
   29)  Consume (CFCs)
   23)  On site radiation testing (make it click like a Geiger counter) 
   13)  Breaking down plastics (look at past presentation)
   44)  Photo-driven battery


   66)  Trace explosive Bacteria
   71)  Bacterial Superglue
   19)  Resistors
   20)  Capacitors (Storing charge)
   55)  Phagocytosis for water in shoes
   56)  Bacterial barometer
   61)  Bacterial paper to print on 
   2)   Active pH buffer for e. coli (target pH)    
   3)   pH meter
   48)  Cilia creating fluid flow, generating fluid current
   50)  Create ferrofluuid to create magnetism
   51)  Bacteria to regulate the temperature of a surface (endothermic and exothermic reaction)
   52)  Long lasting bacterial sunblock
   53)  Bacterial Clothing 
   54)  Thermal heating for toes
   11)  Adjusting Young’s Modulus
   12)  Contracting  group of cells
   14)  Thermometer
   38)  Bacterial film that responds to laser so you can sketch on it. (express GFP light induced 
   45)  Bacterial Gears 


   64)  ELISA for DNA
   65)  ELISA for mRNA
   22)  Magnetic Bacteria 
   27)  Faster biodegradation (Signal activated ) (isn't this environmental?)
   57)  Oncoprotein expressed on the outside missing ligand binding portion
   58)  Cytoskeleton in bacteria
   59)  Engineering current flow  intracellularly
   60)  Bacterial gyroscope
   63)  Bacterias that produce primers
   1)   Proteosome into e. coli design system to keep at steady state to keep e. coli alive
   4)   Nail polish (grow back or fade away)
   6)   Tight junctions into bacteria
   8)   Synthetic Apoptotic signal (and isn't this medical?)
   9)   Music Playing Bacteria: loudspeaker
   46)  Clock using bacterial gears
   47)  Non Newtonian fluid bacteria (using force)
   49)  Bacteria piston using sinking and floating mechanism
   10)  Gap junction music playing
   15)  Rotifers: surviving without water mechanism (protein protection)
   17)  Engineering signal glycoproteins into bacteria (integration of virus disrupts reporter gene)

Round 2: Official 2010 iGEM Draft

Each member chose 3 favorite topics to research

Sean - Opsin, Electrogenesis, Tight Junction

Avi - Proteosome, Storing Charge, Magnetic Field

Ben - Pacemaker, Factor8, Excess Ion uptake

Matt - Self Healing Material, WBC, Bacterial Thermometer

Timi - Splitting Water, Primer Production, Oncoprotein Express

Jeremy - Circadian Rhythm, pH meter, Cytoskeleton

Ragan - Selective Phagocytosis, Erythropoietin Production, Inducible Apoptosis

Round 3: Presentation and Voting

Voted on the basis of: Sexiness, Available Parts, Feasibility, and Applications

Narrowed Down to: Cytoskeleton, Magnetic Bacteria, and Self Healing Armor

Round 4: Group Discussion

Cytoskeleton Discarded

Self-Healing Armor altered to Bacterial Skin

Magnetic Bacteria relegated to side project