Team:Newcastle

From 2010.igem.org

(Difference between revisions)
(Project description)
(Project description)
Line 16: Line 16:
-
To protect the environment our project will also include a design for a [https://2010.igem.org/Team:Newcastle/Non-target-environment_kill_switch| kill switch]. To coordinate the cells(glue production or forming filaments)once they have reached the bottom of the crack, for which Bacillus subtilis 168 required [https://2010.igem.org/Team:Newcastle/Swarming| swarming] genes to be introduced from strain 3610 to swim, we will be using [https://2010.igem.org/Team:Newcastle/End_of_crack_%26_signalling_system| quorum sensing] using the subtilin system previously used by [https://2008.igem.org/Team:Newcastle_University/ProofOfConceptBrick| Newcastle 2008’s iGEM team.]  
+
To protect the environment our project will also include a design for a [https://2010.igem.org/Team:Newcastle/Non-target-environment_kill_switch| kill switch]. To coordinate the cells(glue production or forming filaments)once they have reached the bottom of the crack, for which ''Bacillus subtilis'' 168 required [https://2010.igem.org/Team:Newcastle/Swarming| swarming] genes to be introduced from strain 3610 to swim, we will be using [https://2010.igem.org/Team:Newcastle/End_of_crack_%26_signalling_system| quorum sensing] using the subtilin system previously used by [https://2008.igem.org/Team:Newcastle_University/ProofOfConceptBrick| Newcastle 2008’s iGEM team.]  

Revision as of 12:47, 2 August 2010

iGEM Homepage Newcastle University BacillaFilla Homepage Image Map
Newcastle iGEM Teampic.jpeg


Project description

Microcracks in concrete undermine structural integrity and are inaccessible to conventional repair methods. Bacteria of the Bacillus genus could be the ideal candidates for concrete repair since they are able to precipitate CaCO3 (Use of bacteria to repair cracks in concrete, Tittelboom et al, cement and concrete research (2009)).

Our project aims to fill cracks in concrete with a mixture of:

  • CaCO3 , which has the same expansion coefficient as concrete.
  • Glue, which is required to gel together the CaCO3 crystals.
  • filamentous Bacillus subtilis cells, which will act as reinforcements like the steel fibres found in concrete.


To protect the environment our project will also include a design for a kill switch. To coordinate the cells(glue production or forming filaments)once they have reached the bottom of the crack, for which Bacillus subtilis 168 required swarming genes to be introduced from strain 3610 to swim, we will be using quorum sensing using the subtilin system previously used by Newcastle 2008’s iGEM team.





Newcastle University logo.png    Newcastle cbcb logo.pngNewcastle Biomedicine logo.gif    Team Newcastle CEG logo.gif
Newcastle iww logo.jpg  UNIPV Pavia Logo.gif  Newcastle BBSRC.gif    Newcastle Genevision logo.png Newcastle WelcomeTrust.jpg
FaceBook Icon