Team:NCTU Formosa/Abstract

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  <title>2010 NCTU Formosa--The Mosquito Intelligence Terminator</title>
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          <h1><a href="index.html" title="Go to Start page">2010 NCTU Formosa<span style="font-weight:normal;font-size:50%;">prototype wiki<br>Made In Taiwan</span></a></h1>
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            <h1><strong>Mosquito &bull; Intelligent &bull; Terminator</strong></h1>
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          <h2>The new generation enviroument friendly<br /> pastiside with more controlable<br /> factors and applications</h2>
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              <h1>Mosquito intelligence terminator(MIT)          </h1>
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          <p><span style="font-weight:normal;font-size:130%;"><img src="https://static.igem.org/mediawiki/2010/d/d3/Logo-NCTU.gif" alt="Image description" width="141" height="135" title="Image title" />The  Mosquito Intelligent Terminator (MIT) is designed and optimized to be an ecological and environmental friendly mosquito pesticide. MIT is an  engineered E. coli secreting crystal proteins isolated from Bacillus thuringiensis to kill mosquito larvae, or commonly known as wrigglers. These crystal  proteins are toxic to certain types of mosquitoes  only and are not pathogenic to mammals.  We designed a temperature-dependent genetic  circuit expressing high levels of crystal proteins at room temperature only,  thus production does not occur at incubation temperature. In order to make an  environmentally safe insecticide, our design also incorporates a genetic circuit  controlling the population size of E. coli, thus a surplus will never exist as E.  coli population is self-maintained within the system. This intelligent  terminator is not limited to mosquitos only, as the intelligent terminator system can be custom fitted with  different cry genes to other insect species. Currently, with more than one  hundred crystal proteins targeting various insect species, our design may  potentially serve as a promising pest control solution in the future. </span> </p>
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Revision as of 03:43, 20 October 2010

2010 NCTU Formosa--The Mosquito Intelligence Terminator

Project>Abstract

The Abstract

Mosquito intelligence terminator(MIT)

Image descriptionThe Mosquito Intelligent Terminator (MIT) is designed and optimized to be an ecological and environmental friendly mosquito pesticide. MIT is an engineered E. coli secreting crystal proteins isolated from Bacillus thuringiensis to kill mosquito larvae, or commonly known as wrigglers. These crystal proteins are toxic to certain types of mosquitoes only and are not pathogenic to mammals. We designed a temperature-dependent genetic circuit expressing high levels of crystal proteins at room temperature only, thus production does not occur at incubation temperature. In order to make an environmentally safe insecticide, our design also incorporates a genetic circuit controlling the population size of E. coli, thus a surplus will never exist as E. coli population is self-maintained within the system. This intelligent terminator is not limited to mosquitos only, as the intelligent terminator system can be custom fitted with different cry genes to other insect species. Currently, with more than one hundred crystal proteins targeting various insect species, our design may potentially serve as a promising pest control solution in the future.

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Mosquito • Intelligent • Terminator

The new generation enviroument friendly
pastiside with more controlable
factors and applications



Project>Abstract

The Abstract<a name="ATP"> </a>

Mosquito intelligence terminator(MIT)

<img src="Logo-NCTU.gif" alt="Image description" width="141" height="135" title="Image title" />The Mosquito Intelligent Terminator (MIT) is designed and optimized to be an ecological and environmental friendly mosquito pesticide. MIT is an engineered E. coli secreting crystal proteins isolated from Bacillus thuringiensis to kill mosquito larvae, or commonly known as wrigglers. These crystal proteins are toxic to certain types of mosquitoes only and are not pathogenic to mammals. We designed a temperature-dependent genetic circuit expressing high levels of crystal proteins at room temperature only, thus production does not occur at incubation temperature. In order to make an environmentally safe insecticide, our design also incorporates a genetic circuit controlling the population size of E. coli, thus a surplus will never exist as E. coli population is self-maintained within the system. This intelligent terminator is not limited to mosquitos only, as the intelligent terminator system can be custom fitted with different cry genes to other insect species. Currently, with more than one hundred crystal proteins targeting various insect species, our design may potentially serve as a promising pest control solution in the future.

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