Team:METU Turkey

From 2010.igem.org

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                 <h3>Abstract..</h3>
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                     <p><img src="https://static.igem.org/mediawiki/igem.org/4/4d/MTLogoE-co_sensor.jpg" style="border: 0px solid ; width: 300px; height: 120px; alt="" />Cells can sense and respond to the presence of various gas molecules such as oxygen, nitrogen and carbon monoxide using gas sensor proteins. CooA is a carbon monoxide (CO) sensing transcription factor. It is a member of the cAMP receptor protein (CRP)/fumavate nitrate reduction (FNR) family of transcriptional regulators. CooA switches on oxidation enzymes in Rhodospirillum rubrum (a purple, nonsulfur, phototrophic bacterium) which enables the bacterium to use CO as a carbon source. CO is an odorless and colorless gas which can be extremely lethal. Our aim is to develop a cell sensor which can detect a wide range of CO concentration in the environment. We are building CooA and CooA-responsive promoter biobricks which will be transformed into E.coli. Fluorescent proteins (GFP and RFP) will be utilized as dose-responsive signals of ambient CO.<a href="https://2010.igem.org/Team:METU_Turkey/Project" class="continue">Read More...</a></p>                                         
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                     <p><img src="https://static.igem.org/mediawiki/igem.org/4/4d/MTLogoE-co_sensor.jpg" style="border: 0px solid ; width: 300px; height: 120px; alt="" /> <span style="color:#0A0A2A"> Cells can sense and respond to the presence of various gas molecules such as oxygen, nitrogen and carbon monoxide using gas sensor proteins. CooA is a carbon monoxide (CO) sensing transcription factor. It is a member of the cAMP receptor protein (CRP)/fumavate nitrate reduction (FNR) family of transcriptional regulators. CooA switches on oxidation enzymes in Rhodospirillum rubrum (a purple, nonsulfur, phototrophic bacterium) which enables the bacterium to use CO as a carbon source. CO is an odorless and colorless gas which can be extremely lethal. Our aim is to develop a cell sensor which can detect a wide range of CO concentration in the environment. We are building CooA and CooA-responsive promoter biobricks which will be transformed into E.coli. Fluorescent proteins (GFP and RFP) will be utilized as dose-responsive signals of ambient CO.<a href="https://2010.igem.org/Team:METU_Turkey/Project" class="continue">Read More...</a></p>                                         
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                 <h3>Our Team..</h3>
                 <h3>Our Team..</h3>
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                     <p><img src="https://static.igem.org/mediawiki/igem.org/b/bc/MTteam_cell.jpg" alt="" style="border: 0px solid ; width: 300px; height: 300px;/>METU Turkey is a team consists of advisors and students of Middle East Technical University which are prepared for competing in iGEM 2010. <a href="https://2010.igem.org/Team:METU_Turkey/Team" class="continue">Read More...</a></p></span>
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                     <p><img src="https://static.igem.org/mediawiki/igem.org/b/bc/MTteam_cell.jpg" alt="" style="border: 0px solid ; width: 300px; height: 300px;/>METU Turkey is a team consists of advisors and students of Middle East Technical University which are prepared for competing in iGEM 2010. <a href="https://2010.igem.org/Team:METU_Turkey/Team" class="continue">Read More...</a></p>
                          
                          
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Revision as of 17:23, 23 October 2010

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Abstract..

Cells can sense and respond to the presence of various gas molecules such as oxygen, nitrogen and carbon monoxide using gas sensor proteins. CooA is a carbon monoxide (CO) sensing transcription factor. It is a member of the cAMP receptor protein (CRP)/fumavate nitrate reduction (FNR) family of transcriptional regulators. CooA switches on oxidation enzymes in Rhodospirillum rubrum (a purple, nonsulfur, phototrophic bacterium) which enables the bacterium to use CO as a carbon source. CO is an odorless and colorless gas which can be extremely lethal. Our aim is to develop a cell sensor which can detect a wide range of CO concentration in the environment. We are building CooA and CooA-responsive promoter biobricks which will be transformed into E.coli. Fluorescent proteins (GFP and RFP) will be utilized as dose-responsive signals of ambient CO.Read More...

Our Team..

Read More...