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| - | {{:Team:Imperial_College_London/Templates/Header}}
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| - | {| style="width:900px;background:#f5f5f5;text-align:justify;font-family: helvetica, arial, sans-serif;color:#555555;margin-top:25px;" cellspacing="20"
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| - | |style="font-family: helvetica, arial, sans-serif;font-size:2em;color:#ea8828;"|Signalling Model
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| - | |<html><h2>Objectives</h2></html>
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| - | |<html><h2>Detailed description</h2></html>
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| - | |We assuming steady-state for AIP, Phosphate, ComD and ComE in our cell/in the solution. Hence, we can neglect production and degradation rates of ComD and ComE.
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| - | |'''Equation 1:''' AIP binds to ComD receptor to form a complex (AIP-ComD)
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| - | |AIP + ComD <html>↔</html> AIP-ComD
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| - | |'''Equation 2:''' Phosphate binds to the AIP-ComD complex to form another complex (AIP-ComD*)
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| - | |AIP-ComD + Phosphate <html>↔</html> AIP-ComD*
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| - | |'''Equation 3:''' ComE binds to the AIP-ComD* recepetor to form another complex (AIP-ComD*-ComE)
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| - | |AIP-ComD* + ComE <html>↔</html> AIP-ComD*-ComE
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| - | |'''Equation 4:''' Phosphate group on ComD binds to ComE and forms two products: phosphorylated ComE (ComE*) and AIP-ComD
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| - | |AIP-ComD*-ComE <html>↔</html> AIP-ComD + ComE*
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| - | |<html><h2>Parameters & Constants</h2></html>
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| - | |<html><h2>Results</h2></html>
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| - | |<html><h2>Download Matlab files</h2></html>
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| - | |Using the Law of Mass Action, we can rewrite these 4 equations:
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