Team:Groningen/Home

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The International Genetically Engineered Machine Competition is a annually held synthetic biology competition for undergraduates from all over the world. Teams aim to combine biology and engineering so that they are able to design, create and operate biological circuits within living organisms. Important in this iGEM field of synthetic biology are of course the projects standing on themselves, but synthetic biology is about more than biological systems only: using modelling techniques hypothetical systems can be explored or existing systems optimized, human perspectives are important to asses possibilities of implementing systems in our society and education will help the broader public to gain an understanding of the how's, why's and what's of synthetic biology.
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Surface hydrophobicity is a very useful property and is used in many applications ranging from raincoats, antifouling coatings to applications in the field of medical sciences.
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But most of all iGEM is about fun, creativity and thinking out of the box. That's why the team of Groningen is excited to get started on our project for this years iGEM competition. Our team of 12 undergraduate students will try to create some new perspectives on biological engineering by creating a self assembling hydrophobic biofilm using ''Bacillus subtilis'' colonies.  
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The idea is to engineer a bacterium that once applied to a surface starts forming a fast growing rigid biofilm. The formation will trigger the expression of hydrophobic proteins. These hydrophobic proteins will be incorporated in the biofilm, causing strong hydrophobic surface activity. The result is a  hydrophobic bio-based surface coating.
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For more info, check the [https://2010.igem.org/Main_Page iGEM website] and our first updates on [https://2010.igem.org/Team:Groningen#/project the project] or [https://2010.igem.org/Team:Groningen#/images pictures of our progress]
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Revision as of 20:46, 25 October 2010

Surface hydrophobicity is a very useful property and is used in many applications ranging from raincoats, antifouling coatings to applications in the field of medical sciences.

The idea is to engineer a bacterium that once applied to a surface starts forming a fast growing rigid biofilm. The formation will trigger the expression of hydrophobic proteins. These hydrophobic proteins will be incorporated in the biofilm, causing strong hydrophobic surface activity. The result is a hydrophobic bio-based surface coating.

Groningen-Home-Team.jpg Team. This year a team of young inspired undergraduates from the University of Groningen participated in the amazing challenge of iGEM. A multi-disciplinary team of Molecular Biologists, Chemists, Computer Scientists, Journalists and others spend the summer creating a wonderful project in the emerging field of synthetic biology
Groningen-Home-Model.jpg Model. Using computer models we worked on the frontiers of knowledge. Gene expression was simulated and a simple explanation for cell differentiation was proposed. Also aiding in ethics and practical feasibility a kill switch system was studied. Finally a new standard was proposed for characterizing Biobrick parts so future can be streamlined.
Groningen-Home-Human.jpg Human. Because we believe that synthetic biology can better the lives of people and ensure long term prosperity for all humans we spend time educating high school students. But not all is perfect so risks were assessed and we philosophized on the ethical aspects of synthetic biology.


Our sponsors

Sigma Aldrich DSM NGI GBB Kluyver Center Bioké Stichting biotechnology Nederland (SBN) 101 promotions Center for Synthetic Biology