Team:Groningen

From 2010.igem.org

(Difference between revisions)
(Prototype team page)
 
(93 intermediate revisions not shown)
Line 1: Line 1:
-
<!-- *** What falls between these lines is the Alert Box!  You can remove it from your pages once you have read and understood the alert *** -->
+
__NOTOC__
-
 
+
{{Team:Groningen/Header}}
<html>
<html>
-
<div id="box" style="width: 700px; margin-left: 137px; padding: 5px; border: 3px solid #000; background-color: #fe2b33;">
+
<div id="home">
-
<div id="template" style="text-align: center; font-weight: bold; font-size: large; color: #f6f6f6; padding: 5px;">
+
<div class="textWrapper ajaxWrapper" rel="ajax">
-
This is a template page. READ THESE INSTRUCTIONS.
+
</html>{{:Team:Groningen/Home}}<html>
-
</div>
+
</div>
-
<div id="instructions" style="text-align: center; font-weight: normal; font-size: small; color: #f6f6f6; padding: 5px;">
+
-
You are provided with this team page template with which to start the iGEM season.  You may choose to personalize it to fit your team but keep the same "look." Or you may choose to take your team wiki to a different level and design your own wiki.  You can find some examples <a href="https://2009.igem.org/Help:Template/Examples">HERE</a>.
+
-
</div>
+
-
<div id="warning" style="text-align: center; font-weight: bold; font-size: small; color: #f6f6f6; padding: 5px;">
+
-
You <strong>MUST</strong> have a team description page, a project abstract, a complete project description, a lab notebook, and a safety page.  PLEASE keep all of your pages within your teams namespace. 
+
-
</div>
+
-
</div>
+
-
</html>
+
-
<!-- *** End of the alert box *** -->
+
<br>
-
 
+
</html>
-
 
+
{{Team:Groningen/Footer}}
-
{|align="justify"
+
-
|You can write a background of your team here.  Give us a background of your team, the members, etc.  Or tell us more about something of your choosing.
+
-
|[[Image:Groningen_logo.png|200px|right|frame]]
+
-
|-
+
-
|
+
-
''Tell us more about your project.  Give us background.  Use this as the abstract of your project.  Be descriptive but concise (1-2 paragraphs)''
+
-
|[[Image:Groningen_team.png|right|frame|Your team picture]]
+
-
|-
+
-
|
+
-
|align="center"|[[Team:Groningen | Team Example]]
+
-
|}
+
-
 
+
-
<!--- The Mission, Experiments --->
+
-
 
+
-
{| style="color:#1b2c8a;background-color:#0c6;" cellpadding="3" cellspacing="1" border="1" bordercolor="#fff" width="62%" align="center"
+
-
!align="center"|[[Team:Groningen|Home]]
+
-
!align="center"|[[Team:Groningen/Team|Team]]
+
-
!align="center"|[https://igem.org/Team.cgi?year=2010&team_name=Groningen Official Team Profile]
+
-
!align="center"|[[Team:Groningen/Project|Project]]
+
-
!align="center"|[[Team:Groningen/Parts|Parts Submitted to the Registry]]
+
-
!align="center"|[[Team:Groningen/Modeling|Modeling]]
+
-
!align="center"|[[Team:Groningen/Notebook|Notebook]]
+
-
!align="center"|[[Team:Groningen/Safety|Safety]]
+
-
|}
+

Latest revision as of 17:08, 27 October 2010

iGEM Groningen 2010

Hydrophobofilm
pushing coatings into a greener future

A self assembling bio-based coating is form, a rigid biofilm.
Expression of hydrophobic proteins called chaplins is induced by the biofilm causing strong surface hydrophobicity.
The strongly hydrophobic biofilm will die off by a killswitch, leaving a nice hydrophobic biological coating.

Self assembling hydrophobic biofilm

We aim to design a biological coating as an alternative to for example chemical coatings. For this we, unconventionally, utilized a Bacillus subtilis biofilm. We wanted to enable our biofilm to be equipped with an interesting property which is automatically initiated. So we introduced an expression trigger which relies on quorum sensing. Our project was directed at finding an alternate solution to biofouling, since regular, chemical coatings which are widely in use pose a threat to the environment. In nature the lotus leaves show self-cleansing properties ascribed to their extreme surface hydrophobicity. In the prokaryotic domain we stumbled upon chaplins, strongly hydrophobic proteins originating from Streptomyces coelicolor. Surface hydrophobicity is a very useful property and is used in many applications ranging from not only antifouling coatings but also other applications which require water repellence to applications in the field of medical sciences. During our project we have contributed to the parts registry whit numerous BioBricks.


We believe that there is a great future for biological coatings as demonstrated within the project. Hydrophobic biological coatings can provide a greener antifouling solution. However using the underlying mechanisms of biofilm triggered expression for other systems like dynamic painting, sensing of environmental changes or even the integration with silicon chips might be within the realm of possibilities. So we challenge coming iGEM teams to further explore and brainstorm about the possibilities of using biofilms as a host for a wide range of applications.

Team
This year a team of young inspired undergraduates from the [http://www.rug.nl University of Groningen] participated in the amazing challenge of iGEM. A multi-disciplinary team of Molecular Biologists, Chemists, Computer Scientists, Journalists and others spend the summer creating a wonderful project in the emerging field of synthetic biology
Modeling
Using computer models we worked on the frontiers of knowledge. Gene expression was simulated and a simple explanation for cell differentiation was proposed. Also aiding in ethics and practical feasibility a kill switch system was studied. Finally a new standard was proposed for characterizing Biobrick parts so future can be streamlined.
Human Practices
Because we believe that synthetic biology can better the lives of people and ensure long term prosperity for all humans we spend time educating high school students. But not all is perfect so risks were assessed and we philosophized on the ethical aspects of synthetic biology.


Our sponsors

Sigma Aldrich DSM NGI GBB Kluyver Center Bioké Stichting biotechnology Nederland (SBN) 101 promotions Center for Synthetic Biology