Team:ESBS-Strasbourg/Project/Application
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- | <li><a href="#knock"> | + | <li><a href="#knock">Protein analysis</a></li> |
<li><a href="#flip">Flip Flop</a></li> | <li><a href="#flip">Flip Flop</a></li> | ||
<li><a href="#geneos">Genetic Oscillator </a></li> | <li><a href="#geneos">Genetic Oscillator </a></li> | ||
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<p><b>Genetic Oscillator</b></p> | <p><b>Genetic Oscillator</b></p> | ||
The idea of the flip flop mechanism can be extended to a genetic oscillator with three, four or even more sequential steps. Such an implementation would present a genetically encoded device to store multiple bits of information within a living cell.<br> | The idea of the flip flop mechanism can be extended to a genetic oscillator with three, four or even more sequential steps. Such an implementation would present a genetically encoded device to store multiple bits of information within a living cell.<br> | ||
- | Natural oscillator circuits are autonomous | + | Natural oscillator circuits are autonomous orchestrating periodic inductions of specific target genes and are found in central and peripheral circadian clocks <i><a href="https://2010.igem.org/Team:ESBS-Strasbourg/Project/Reference">[38]</a></i>. Many physiological activities are coordinated by circadian pacemakers <i><a href="https://2010.igem.org/Team:ESBS-Strasbourg/Project/Reference">[43],[44]</a></i>, making them particular interesting. Synthetic oscillator circuits which mediate protein expression dynamics could provide new insights into protein networks of by simulating natural conditions. <br> |
<br> | <br> | ||
Figure 3 shows an example of a three step oscillator. This oscillator is tightly controlled by light and allows the sequentially expression of three different genes. | Figure 3 shows an example of a three step oscillator. This oscillator is tightly controlled by light and allows the sequentially expression of three different genes. |
Latest revision as of 00:15, 28 October 2010
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