Team:Cambridge/HIV Diagnosis

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=HIV Diagnosis=
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One of the projects that the Cambridge team considered was to replace the [http://en.wikipedia.org/wiki/ELISA ELISA] currently used for HIV diagnosis with a single celled biosensor.  This would have a number of advantages:
One of the projects that the Cambridge team considered was to replace the [http://en.wikipedia.org/wiki/ELISA ELISA] currently used for HIV diagnosis with a single celled biosensor.  This would have a number of advantages:
*Cheap, simply taking a sample from a fermenter
*Cheap, simply taking a sample from a fermenter
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*Activation of the peptide signal receptor would trigger the production of a coloured pigment output via a sensitivity tuner.
*Activation of the peptide signal receptor would trigger the production of a coloured pigment output via a sensitivity tuner.
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The most challenging aspect was finding an appropriate large peptide and receptor.  The most promising was a yeast mating hormone (used in yeast) but we concluded that the processing of this small peptide would likely by affected by it's fusion to other hormones and abandoned the idea. If this could be overcome we believe the project might have a lot  of potential
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The most challenging aspect was finding an appropriate large peptide and receptor.  The most promising was a yeast mating hormone (used in yeast) but we concluded that the processing of this small peptide would likely by affected by it's fusion to other hormones and abandoned the idea. If this could be overcome we believe the project might have a lot  of potential.
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Latest revision as of 23:47, 10 August 2010