Team:Cambridge/Bioluminescence

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The Cambridge team for this year's iGEM is aiming to improve the production of light by engineered micro-organisms.  We are pursuing a number of lines of enquiry to achieve this
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The Cambridge team for this year's iGEM is aiming to improve the production of light by engineered micro-organisms.  We are pursuing a number of lines of enquiry to achieve this:
* <strong>Bacterial luciferases</strong> from <i>Vibrio fischeri</i>, and <i>Photorhabdus luminescens</i>
* <strong>Bacterial luciferases</strong> from <i>Vibrio fischeri</i>, and <i>Photorhabdus luminescens</i>
* <strong>Firefly luciferases</strong> from <i>Photinus pyralis</i>, and <i>Luciola cruciata</i>, including mutants with increased light output and different colours
* <strong>Firefly luciferases</strong> from <i>Photinus pyralis</i>, and <i>Luciola cruciata</i>, including mutants with increased light output and different colours
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* Implementation of the firefly <b>luciferin regenerating enzymes (LRE)</b> from the above species into E. coli
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* Implementation of the firefly <b>luciferin regenerating enzymes (LRE)</b> from the above species into <i>E. coli</i>, this enzyme is believed to
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[[Image:Cam-luci-cycle.jpg|center|500px]]
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Revision as of 19:48, 3 August 2010