http://2010.igem.org/wiki/index.php?title=Talk:Team:Groningen&feed=atom&action=historyTalk:Team:Groningen - Revision history2024-03-29T12:01:18ZRevision history for this page on the wikiMediaWiki 1.16.5http://2010.igem.org/wiki/index.php?title=Talk:Team:Groningen&diff=31114&oldid=prevJoelkuiper: Removing all content from page2010-07-22T20:34:10Z<p>Removing all content from page</p>
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<td colspan='2' style="background-color: white; color:black;">Revision as of 20:34, 22 July 2010</td>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">{{Team:Groningen/Header}}</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">Food</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-Food: loose weight consumes fat and chlorestorial</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">We could design probiotic bacteria (Like that useless Actimel crap but useful!! Imagine that!!1!) which are destined to waste a certain amount of calories. They would be eaten added to yoghurt or the like (In contrast to Actimel we could even make it tasty). So lets say for some reason you feel like not becoming a diabetic or a heart attack victim, you just compensate all the extra calories by munching our genetically modified never tested on animals or the like bacteria which we only have a vague idea of what they might do and TARAAA! Technology beats nature… again. The easiest would be to get the bacteria to produce something that can’t be digested in the intestines like fat or even better, a substance that smells good (for obvious reasons) After a while the indigenous bacteria will outcompete our sissy lab bacteria and everything is back to normal –Ramon Sieber</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-bacteria changing the taste of yogurt</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-detect bad milk bacteria</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-vitamine rich food , nice tasting food</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-Bacteria that import vitamins or minerals and inject them into plant cells to make them more nutritional.</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-Alcohol content controll by apoptosis</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">Right now alcohol content is controlled either by sugar availability, cytotoxicity, or manual killing of the yeast at a certain alcohol level (the idea could be applied to other fermentation products as well). It would be usefull to have a system in which you could decide beforehand to which degree the yeast will grow, this could be done by getting the yeast to recognize a certain ratio between alcohol and a second substance and kill themselves once that ratio is reached. By dosing that second substance it could be determined when the yeast starts killing itself and hence the final alcohol level. - Ramon Sieber</del></div></td><td colspan="2"> </td></tr>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">Techology</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-Laundry machine -> encymes producing bacteria for washing machines</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-Sponge - ISOLATION</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-biological Anti freeze so it can detect temperature change and unfreeze for example the car window.</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-Use bacteria as a memory/harddisk ->Computer by Bacteria</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-Synthetic biomolecules on synthetic biomolecules</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-Magnetic bacteria-two bacteria spin around each other and create a magnetic field,which we can measure(*)</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-Detecting clusters of bacteria</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-biocamera( there are bacteria which sensitivi different kind of signal, when they are exposed, they are giving a shape on the medium (take pic!)</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-molecular fishing rod</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">Using the Biotin – Avidin connection bacterias could maybee ( I don’t know how strong that connection really is, but it is the strongest at hand) be bound to a surface or the like. The bacteria could express biotin or avidin to the surface (the bricks exist) at a certain metabolic state, on command, as long as they are allive, when you flash them with light or whatever… and then be fished out of the solution with a device coated with Biotin or avidin. -Ramon Sieber</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-UV detecting bacteria</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-biofilm color</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-Detection of movement</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">A system consisting of two organisms, a) Bacteria and b) a creature abel to move over solid surface (Amoeba, nematode, snail…) . The bacteria would cover the ground (agar plate) completely and would detect the organism moving over them, either by a chemical which this organism releases or by pressure, depending on size of the moving agent pressure might not work, and start to produce a fluorescent or colour signal hence leaving a mark of the organisms way (I know snails do that anyway but…) Using chemotaxis the organisms could be sent through a maze or be steered in order to gain world domination.</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">- The tron version of movement detection</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">In addition to a colour or fluorescence marker the bacteria also produce a repellent for the used organism. This will hinder the organism of crossing its own path or the path of another “Player”. Which basically is what Tron does. For all sorry souls who have never played it: http://gamepuma.com/action-games/Tron.html -Ramon Sieber</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-biofilm insulating bacteria (bacteria cover the building)</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-anti-rust bacteria</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-two component gene made by bacteria stolling factor</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-keyboard( pressure sensitive bacteria)</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-gas transporter bacteria</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-filter bacteria</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-bioglue</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-seismo detecting bacteria(sound detecting bacteria)</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-carbon tubes producing bacteria</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-flying and ozone producing bacteria</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-spore eating bacteria</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">Environment</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-Biodegradable fabric: good & green</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-Fertilizing Gounds: cactus, nitrogen fixing compatible to all plants</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-Bacteria to reduce air pollution</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-Oil spill responce - Baceria cleaning it up.</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">After oil spills the oil which is not removed mechanically is mostly degraded by bacteria (bioremediation) so far only adding fertilizer seems to help, the addition of living bacteria has mostly not shown any effect. I can think of three ways to use bacteria in order to improve bioremediation, 1: Nitrogen fixing bacteria could be added instead of fertilizer, Nitrogen fixing bacteria already exist, but I don’t know if they can life in oily environements. 2. Bacteria which can metabolize the compounds which so far can not be degraded by bacteria 3. Bacteria which are actually better at degrading oil than existing ones ( I have however no clue how that could be achived) 1&3 would enhance speed, 2 would improve endpiont which has so far not been attempted (at least not from what I have read) -Marine microorganisms make a meal out of oil, nature reviews 2006 -Field evaluation of marine oil spill bioremediation, microbial reviews 1996 (Very long but also very complete review about the topic) -Ramon Sieber</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-anti-acidification bacteria for ocean</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-plactic degrading bacteria(microplastic degrading bacteria): We've been beaten by puberty: http://www.wired.com/wiredscience/2008/05/teen-decomposes/,</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">Health</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-Bacteria -> Colon Cancer</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">First of all you need to think of what cells you’d want to detect: stem cells could be interesting Identification of Gastric Cancer Stem Cells Using the Cell Surface Marker CD44-Takaishi, but of course a stem cell is just that, there is no cancer yet. (also: Phenotypic characterization of human colorectal cancer stem cells - Dalerba) A lot of different markers: http://www.antibodybeyond.com/reviews/tumor-markers/colorectal-cancer-marker.htm, FAS overexpression could be a good one too. http://www.tc-cancer.com/tumormarkers.html</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">Als interesting: The effect of certain gut bacteria on the development and maybe progression of colon cancer: Probiotics. These characterisation might help choose a test model. http://www.google.nl/search?hl=nl&q=bacteria+apoptosis+cancer+cells+colon&meta=&aq=f&aqi=&aql=&oq=&gs_rfai= E.coli is able to do this via BMP2 for example and human proteins that have alike functions can ofcourse all be produced in E.Coli.</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">Dangers: Infections</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-bacteria that has a capable of altering one type of aa to another or producing essential amino acid</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-anti-stress bacteria</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-maleria repelling bacteria</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-anti-hangover bacteria</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-quit smoking bacteria</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-bacteria against the skin disease</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-melanin production stimulating baceria</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">Miscellanious</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-making a bacterial community( to mimic the interaction between bacteia in real world) (http://www.blc.arizona.edu/courses/mcb572/pdfs%202007/design%20principles%20in%20bacteria2005.pdf is good for bacterail community, may be useful to check:) ) (I also found a reserch about the chemotaxis signaling of E.coli is related with both our "maleria repellent bacteria" and bacterial community idea so i m sharing a useful website in here: http://132.77.150.57/mcb/UriAlon/Papers/Nature397_168.pdf May be, you can read and we may decide that for which idea we can apply and get better result:) )</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-restore gulf stream pump once it breakes down</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-smelling (coffee) of circadian rythm bacteria</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">Cells which react to a long period of darkness (night) followed by light (the sensors for light exist so this should be possible) produce either smell of coffe or caffein (your blanket is a biofilm so you absorbe it) to assure a gentle awakening –Ramon Sieber</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-timer bacteria</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">The bacterio'clock is not a new idea. Godfathers of synthetic oscilator systems: Elowitz and Leibler and their repressilator system. What would be interesting is to try and make a system that responds to certain cue's or produces something like an aroma or medicin. Or a brand new system, to submit awesome new biobricks and systems. A circadian rythm or a rythm to adjust bacterial or yeast behaviour. Previous iGEM projects: Paris08, Shanghai09, Michigan 2008 (the sequencilator or something like that). Martha Merrow was enthousiastic about a possible project and offered advice. Also interesting: oscillating systems. http://www.nature.com/nature/journal/v463/n7279/full/nature08753.html - Peter Roemers</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-caffeine producing bacteria</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-glitter bacteria</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-sparkling bacteria</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-caffeine biobrick</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-cake degrading bacteria</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">- Anti-body binding bacteria: for numerous functions, targeted that is</del></div></td><td colspan="2"> </td></tr>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">@Home ideas (Maarten):</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">-Make bacteria produce a certain compound (like a pigment) which you'll want to apply to a surface of some sort. Let them first produce it cytosolic and then let them secrete it by a light sensitive channel. These channels are the MscL (Mechanoselective channels of Large conductance) and have been modified to be light and pH sensitive in stead (A. Koçer, 2007). I think we can use this mechanism for several for our ideas, e.g. biofilm paint and the detection of cancerous cells, which have a lower pH when compared to normal cells. The bacteria (for cancer in the GI tract) could then secrete some sort of detectable marker. Lipid bodies could be used for detection in the rest of the body.</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">{{Team:Groningen/Footer}}</del></div></td><td colspan="2"> </td></tr>
</table>Joelkuiperhttp://2010.igem.org/wiki/index.php?title=Talk:Team:Groningen&diff=1847&oldid=prevAslomp at 19:56, 9 April 20102010-04-09T19:56:11Z<p></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Food</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Food</div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>-Make bacteria produce a certain compound (like a pigment) which you'll want to apply to a surface of some sort. Let them first produce it cytosolic and then let them secrete it by a light sensitive channel. These channels are the MscL (Mechanoselective channels of Large conductance) and have been modified to be light and pH sensitive in stead (A. Koçer, 2007). I think we can use this mechanism for several for our ideas, e.g. biofilm paint and the detection of cancerous cells, which have a lower pH when compared to normal cells. The bacteria (for cancer in the GI tract) could then secrete some sort of detectable marker. Lipid bodies could be used for detection in the rest of the body.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>-Make bacteria produce a certain compound (like a pigment) which you'll want to apply to a surface of some sort. Let them first produce it cytosolic and then let them secrete it by a light sensitive channel. These channels are the MscL (Mechanoselective channels of Large conductance) and have been modified to be light and pH sensitive in stead (A. Koçer, 2007). I think we can use this mechanism for several for our ideas, e.g. biofilm paint and the detection of cancerous cells, which have a lower pH when compared to normal cells. The bacteria (for cancer in the GI tract) could then secrete some sort of detectable marker. Lipid bodies could be used for detection in the rest of the body.</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">{{Team:Groningen/Footer}}</ins></div></td></tr>
</table>Aslomphttp://2010.igem.org/wiki/index.php?title=Talk:Team:Groningen&diff=1846&oldid=prevAslomp at 19:54, 9 April 20102010-04-09T19:54:35Z<p></p>
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</table>Aslomphttp://2010.igem.org/wiki/index.php?title=Talk:Team:Groningen&diff=1212&oldid=prevPtr at 16:44, 28 March 20102010-03-28T16:44:56Z<p></p>
<a href="http://2010.igem.org/wiki/index.php?title=Talk:Team:Groningen&diff=1212&oldid=1063">Show changes</a>Ptrhttp://2010.igem.org/wiki/index.php?title=Talk:Team:Groningen&diff=1063&oldid=prevNeima at 15:45, 23 March 20102010-03-23T15:45:37Z<p></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>-making a bacterial community( to mimic the interaction between bacteia in real world)</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>-making a bacterial community( to mimic the interaction between bacteia in real world)</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">(http://www.blc.arizona.edu/courses/mcb572/pdfs%202007/design%20principles%20in%20bacteria2005.pdf is good for bacterail community, may be useful to check:) )</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">(I also found a reserch about the chemotaxis signaling of E.coli is related with both our "maleria repellent bacteria" and bacterial community idea so i m sharing a useful website in here: http://132.77.150.57/mcb/UriAlon/Papers/Nature397_168.pdf</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">May be, you can read and we may decide that for which idea we can apply and get better result:) ) </ins></div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>-biocamera( there are bacteria which sensitivi different kind of signal, when they are exposed, they are giving a shape on the medium (take pic!)</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>-biocamera( there are bacteria which sensitivi different kind of signal, when they are exposed, they are giving a shape on the medium (take pic!)</div></td></tr>
</table>Neimahttp://2010.igem.org/wiki/index.php?title=Talk:Team:Groningen&diff=1058&oldid=prevPtr at 14:22, 23 March 20102010-03-23T14:22:13Z<p></p>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>-plactic degrading bacteria(microplastic degrading bacteria)</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>-plactic degrading bacteria(microplastic degrading bacteria)<ins class="diffchange diffchange-inline">:</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">We've been beaten by puberty: http://www.wired.com/wiredscience/2008/05/teen-decomposes/, </ins></div></td></tr>
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</table>Ptrhttp://2010.igem.org/wiki/index.php?title=Talk:Team:Groningen&diff=1055&oldid=prevPtr at 13:57, 23 March 20102010-03-23T13:57:28Z<p></p>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>-Bacteria -> Colon Cancer <del class="diffchange diffchange-inline">DETECTION</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>-Bacteria -> Colon Cancer </div></td></tr>
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<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">First of all you need to think of what cells you''d want to detect: stem cells could be interesting ''Identification of Gastric Cancer Stem Cells Using the Cell Surface Marker CD44-Takaishi'', but of course a stem cell is just that, there is no cancer yet. (also: Phenotypic characterization of human colorectal cancer stem cells - Dalerba) A lot of different markers: http://www.antibodybeyond.com/reviews/tumor-markers/colorectal-cancer-marker.htm, FAS overexpression could be a good one too. http://www.tc-cancer.com/tumormarkers.html </ins></div></td></tr>
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<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">Als interesting: The effect of certain gut bacteria on the development and maybe progression of colon cancer: Probiotics. These characterisation might help choose a test model. http://www.google.nl/search?hl=nl&q=bacteria+apoptosis+cancer+cells+colon&meta=&aq=f&aqi=&aql=&oq=&gs_rfai= E.coli is able to do this via BMP2 for example and human proteins that have alike functions can ofcourse all be produced in E.Coli.</ins></div></td></tr>
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<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">Dangers: Infections</ins></div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>-Laundry machine -> encymes producing bacteria for washing machines</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>-Laundry machine -> encymes producing bacteria for washing machines</div></td></tr>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>The bacterio'clock is not a new idea. Godfathers of synthetic oscilator systems: Elowitz and Leibler and their repressilator system. What would be interesting is to try and make a system that responds to certain cue's or produces something like an aroma or medicin. Or a brand new system, to submit awesome new biobricks and systems. A circadian rythm or a rythm to adjust bacterial or yeast behaviour. Previous iGEM projects: Paris08, Shanghai09. Martha Merrow was enthousiastic about a possible project and offered advice. Also interesting: oscillating systems. http://www.nature.com/nature/journal/v463/n7279/full/nature08753.html - Peter Roemers</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>The bacterio'clock is not a new idea. Godfathers of synthetic oscilator systems: Elowitz and Leibler and their repressilator system. What would be interesting is to try and make a system that responds to certain cue's or produces something like an aroma or medicin. Or a brand new system, to submit awesome new biobricks and systems. A circadian rythm or a rythm to adjust bacterial or yeast behaviour. Previous iGEM projects: Paris08, Shanghai09<ins class="diffchange diffchange-inline">, Michigan 2008 (the sequencilator or something like that)</ins>. Martha Merrow was enthousiastic about a possible project and offered advice. Also interesting: oscillating systems. http://www.nature.com/nature/journal/v463/n7279/full/nature08753.html - Peter Roemers</div></td></tr>
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</table>Ptrhttp://2010.igem.org/wiki/index.php?title=Talk:Team:Groningen&diff=1044&oldid=prevPtr at 13:33, 23 March 20102010-03-23T13:33:17Z<p></p>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>The bacterio'clock is not a new idea. Godfathers of synthetic oscilator systems: Elowitz and Leibler and their repressilator system. What would be interesting is to try and make a system that responds to certain cue's or produces something like an aroma or medicin. Or a brand new system, to submit awesome new biobricks and systems. A circadian rythm or a rythm to adjust bacterial or yeast behaviour. Previous iGEM projects: Paris08, Shanghai09. Martha Merrow was enthousiastic about a possible project and offered advice. - Peter Roemers</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>The bacterio'clock is not a new idea. Godfathers of synthetic oscilator systems: Elowitz and Leibler and their repressilator system. What would be interesting is to try and make a system that responds to certain cue's or produces something like an aroma or medicin. Or a brand new system, to submit awesome new biobricks and systems. A circadian rythm or a rythm to adjust bacterial or yeast behaviour. Previous iGEM projects: Paris08, Shanghai09. Martha Merrow was enthousiastic about a possible project and offered advice. <ins class="diffchange diffchange-inline">Also interesting: oscillating systems. http://www.nature.com/nature/journal/v463/n7279/full/nature08753.html </ins>- Peter Roemers</div></td></tr>
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</table>Ptrhttp://2010.igem.org/wiki/index.php?title=Talk:Team:Groningen&diff=1042&oldid=prevPtr at 13:29, 23 March 20102010-03-23T13:29:24Z<p></p>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>The bacterio'clock is not a new idea. Godfathers of synthetic oscilator systems: Elowitz and Leibler and their repressilator system. What would be interesting is to try and make a system that responds to certain cue's or produces something like an aroma or medicin. <del class="diffchange diffchange-inline">Acircadian </del>rythm or a rythm to adjust bacterial or yeast behaviour. </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>The bacterio'clock is not a new idea. Godfathers of synthetic oscilator systems: Elowitz and Leibler and their repressilator system. What would be interesting is to try and make a system that responds to certain cue's or produces something like an aroma or medicin. <ins class="diffchange diffchange-inline">Or a brand new system, to submit awesome new biobricks and systems. A circadian </ins>rythm or a rythm to adjust bacterial or yeast behaviour. <ins class="diffchange diffchange-inline">Previous iGEM projects: Paris08, Shanghai09. Martha Merrow was enthousiastic about a possible project and offered advice. - Peter Roemers</ins></div></td></tr>
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</table>Ptrhttp://2010.igem.org/wiki/index.php?title=Talk:Team:Groningen&diff=1034&oldid=prevPtr at 12:53, 23 March 20102010-03-23T12:53:39Z<p></p>
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<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">The bacterio'clock is not a new idea. Godfathers of synthetic oscilator systems: Elowitz and Leibler and their repressilator system. What would be interesting is to try and make a system that responds to certain cue's or produces something like an aroma or medicin. Acircadian rythm or a rythm to adjust bacterial or yeast behaviour. </ins></div></td></tr>
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