Project/SpooA/

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=== Testing and verification ===
=== Testing and verification ===
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=== References ===
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[1] Lereclus D., Agaisse H., Grandvalet C., Salamitou S. & Gominet M. (2000), Regulation of toxin and virulence gene transcription in Bacillus thuringiensis. Int. J. Med. Microbiol. '''290:'''295-299.

Revision as of 16:58, 24 October 2010


Contents

SpooA repressor - BBa_K354004

BioBrick Background

So as to inhibit the transcription driven by the PlcR promoter, the SpoOA protein binds to a particular sequence. Binding to this region prevents polymerase from properly interacting with the promoter and thus represses transcription. The regions within the PlcR promoter that SpoOA binds are referred to as the SpoOA boxes, of which, two of these boxes flank the PlcR-PapR positive regulator binding site thus repressing transcription [1].

Sequence and Annotation


Testing and verification


References

[1] Lereclus D., Agaisse H., Grandvalet C., Salamitou S. & Gominet M. (2000), Regulation of toxin and virulence gene transcription in Bacillus thuringiensis. Int. J. Med. Microbiol. 290:295-299.